US2009264341A1PendingUtilityA1

Purified arabinogalactan-protein (agp) composition useful in the treatment psoriasis and other disorders

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Assignee: LUPIN LTDPriority: Sep 1, 2004Filed: Jul 2, 2009Published: Oct 22, 2009
Est. expirySep 1, 2024(expired)· nominal 20-yr term from priority
A61P 37/08A61P 37/06A61P 29/00A61P 25/00A61P 19/02A61K 36/66A61P 17/04A61P 17/06A61P 11/00A61P 11/06A61P 1/04C07K 14/415Y02A50/30
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Claims

Abstract

A purified Arabinogalactan-Protein (AGP) composition isolated through a selective method from the leaves and/or stems of Argemone mexicana plant is described. Also described is a purified Arabinogalactan-Protein (AGP) composition isolated from the leaves and/or stems of Argemone mexicana plant, which has one or more of the following effects: immunosuppression, lymphoproliferation inhibition, cytokine modulation such as IL-2 inhibition, IFN-γ inhibition, or IL-10 induction; keratinocyte proliferation inhibition, keratolytic activity and inhibitory activity in Mouse Ear Swelling test (MEST).

Claims

exact text as granted — not AI-modified
1 - 58 . (canceled) 
   
   
       59 . A purified Arabinogalactan Protein (AGP) composition, having an average molecular weight range between 10 KD to 150 KD, isolated from the leaves, stems or both of  Argemone mexicana  plant. 
   
   
       60 . A pharmaceutical composition comprising a therapeutically effective amount of the purified Arabinogalactan Protein (AGP) of  claim 59  and a pharmaceutically acceptable excipient. 
   
   
       61 - 89 . (canceled)

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