US2009299066A1PendingUtilityA1

Triazolone derivatives as mmp inhibitors for the treatment of asthma and copd

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Assignee: ERIKSSON ANDERSPriority: Mar 30, 2004Filed: Aug 10, 2009Published: Dec 3, 2009
Est. expiryMar 30, 2024(expired)· nominal 20-yr term from priority
Inventors:Anders ErikssonMatti Lepisto
A61P 43/00C07D 417/14A61P 11/00C07D 491/10C07D 249/12C07D 401/12C07D 401/14A61P 11/06
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Abstract

The invention provides compounds of formula (I): wherein R 1 , R 2 , R 3 , R 4 , R 5 , X, Y, L, G 1 and m have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceuticals compositions; and their use in therapy. The compounds are useful as metalloproteinase (MMP) inhibitors.

Claims

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1 - 17 . (canceled) 
   
   
       18 . 2-Cyclopropyl-5-(1,2,3,6-tetrahydropyridin-4-ylethynyl)pyrimidine trifluoroacetate.

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