US2009311353A1PendingUtilityA1

Equal-containing fermentation product of soybean embryonic axis, and method for production thereof

Assignee: OTSUKA PHARMA CO LTDPriority: Dec 6, 2005Filed: Dec 5, 2006Published: Dec 17, 2009
Est. expiryDec 6, 2025(expired)· nominal 20-yr term from priority
A61P 5/32A61P 5/30A61P 7/10A61P 3/06A61P 35/00A61P 3/04A61P 25/24A61P 3/00A61P 15/12A61P 13/08A61P 19/10A61P 1/00A61P 15/00A61K 2800/85A23V 2002/00A61K 31/352A61Q 19/10A23L 33/105A61K 8/9789A61Q 19/02A61K 36/48A61K 8/97A61K 8/498A61Q 19/00A61K 2236/19A23L 11/50A23V 2400/21A23L 11/07A23L 33/10A23V 2250/21172A23V 2250/0636
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Claims

Abstract

An object of the invention is to provide an equol-containing fermented soybean hypocotyl material that is useful for foods, pharmaceutical preparations, cosmetic products, etc. The equol-containing fermented soybean hypocotyl material of the invention is obtained by fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein.

Claims

exact text as granted — not AI-modified
1 . An equol-containing fermented soybean hypocotyl material obtained by fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein. 
   
   
       2 . A fermented soybean hypocotyl material according to  claim 1 , wherein said at least one microorganism is a lactic acid bacterium of the genus  Lactococcus.    
   
   
       3 . A fermented soybean hypocotyl material according to  claim 1 , wherein said at least one microorganism belongs to  Lactococcus garvieae.    
   
   
       4 . A fermented soybean hypocotyl material according to  claim 1 , which contains 0.1 to 20 wt % of equol per total weight of dry fermented soybean hypocotyl material. 
   
   
       5 . A fermented soybean hypocotyl material according to  claim 1 , which further contains daidzin compounds, genistin compounds, genistei compounds, glyciti compounds and glycitei compounds. 
   
   
       6 . A fermented soybean hypocotyl material according to  claim 1 , which further contains ornithine. 
   
   
       7 . A food containing a fermented soybean hypocotyl material of  claim 1 . 
   
   
       8 . A food according to  claim 7 , which is a dietary supplement. 
   
   
       9 . A food according to  claim 7 , which contains 0.1 to 90 g of the fermented soybean hypocotyl material per 100 g of the food. 
   
   
       10 . A pharmaceutical preparation containing a fermented soybean hypocotyl material of  claim 1 . 
   
   
       11 . A pharmaceutical preparation according to  claim 10 , which is used for preventing or treating menopausal disorders, osteoporosis, prostatic hypertrophy, or metabolic syndrome. 
   
   
       12 . A pharmaceutical preparation according to  claim 10 , which is used for lowering the blood cholesterol level. 
   
   
       13 . Use of a fermented soybean hypocotyl material of  claim 1  for producing preparations for preventing or treating menopausal disorders, osteoporosis, prostatic hypertrophy, or metabolic syndrome. 
   
   
       14 . Use of a fermented soybean hypocotyl material of  claim 1  for producing preparations for lowering the blood cholesterol level. 
   
   
       15 . A method for treating menopausal disorders comprising the step of administering an effective amount of a fermented soybean hypocotyl material of  claim 1  to a patient suffering from menopausal disorders. 
   
   
       16 . A method for lowering the blood cholesterol level comprising the step of administering an effective amount of a fermented soybean hypocotyl material of  claim 1  to a patient who is in need of lowering the blood cholesterol level. 
   
   
       17 . A cosmetic product containing the fermented soybean hypocotyl material of  claim 1 . 
   
   
       18 . A cosmetic product according to  claim 17 , which contains 0.1 to 10 g of the fermented soybean hypocotyl material per 100 g of cosmetic product. 
   
   
       19 . A method for producing an equol-containing fermented soybean hypocotyl material comprising the step of fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein.

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