US2009326239A1PendingUtilityA1
Fermentative preparation process for and crystal forms of cytostatics
Est. expiryFeb 19, 2018(expired)· nominal 20-yr term from priority
Inventors:Hans HofmannMarion MahnkeKlaus MemmertFrank PetersenThomas SchuppErnst KustersMichael Mutz
A61P 43/00A61P 35/04A61P 35/00C07K 2299/00C12P 17/167C07D 493/04C07D 417/14C12P 17/181C12P 17/18C12R 2001/01C12N 1/205
60
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
The invention relates to a new process for concentrating epothilones in culture media, a new process for the production of epothilones, a new process for separating epothilones A and B and a new strain obtained by mutagenesis for the production of epothilones, as well as aspects related thereto. New crystal forms of epothilone B are also described.
Claims
exact text as granted — not AI-modified1 . A method of separating epothilones from one another using chromatography on a reversed-phase column with an eluant containing a lower alkyl-cyanide.
2 . A method according to claim 2 , herein a column material is used which is charged with hydrocarbon chains containing 18 carbon atoms, and the eluant used is a mixture of water and acetonitrile.Join the waitlist — get patent alerts
Track US2009326239A1 — get alerts on status changes and closely related new filings.
We store only your email — no account needed. See our privacy policy.