Implantable support device with graft

Abstract

Implantable medical devices comprising a support frame and a graft member attached to the support frame. The support frame can define one or more structural features that substantially prevent migration of the graft member along the support frame.

1 . An implantable medical device, comprising:
 an expandable support frame having a first end, a second end, a surface, and a plurality of struts interconnected by bends;   a first series of barbs disposed at the first end of the expandable support frame and extending in a first direction;   a second series of barbs disposed at the second end of the expandable support frame and extending in a second, different direction; and   a graft member attached to the support frame;   wherein each barb of the first and second series of barbs extends away from the surface of the expandable support frame and through the graft member.   
   
   
       2 . The implantable medical device according to  claim 1 , wherein the first direction is substantially opposite the second direction. 
   
   
       3 . The implantable medical device according to  claim 1 , wherein the expandable support frame is adapted such that the first and second ends of the support frame are brought near each other when the implantable medical device is positioned within a vessel such that the barbs of the first series of barbs and the barbs of the second series of barbs extend in the same direction. 
   
   
       4 . The implantable medical device according to  claim 1 , further comprising a third series of barbs disposed at the first end of the expandable support frame and extending in a third direction that is different than the first direction. 
   
   
       5 . The implantable medical device according to  claim 4 , wherein each barb of the third series of barbs extends away from the surface of the expandable support frame and through the graft member. 
   
   
       6 . The implantable medical device according to  claim 4 , further comprising a fourth series of barbs disposed at the second end of the expandable support frame and extending in a fourth direction that is different than the second direction. 
   
   
       7 . The implantable medical device according to  claim 6 , wherein each barb of the fourth series of barbs extends away from the surface of the expandable support frame and through the graft member. 
   
   
       8 . The implantable medical device according to  claim 1 , wherein the expandable support frame is self-expandable. 
   
   
       9 . The implantable medical device according to  claim 1 , wherein the expandable support frame is balloon-expandable. 
   
   
       10 . The implantable medical device according to  claim 1 , wherein the expandable support frame is formed from wire. 
   
   
       11 . The implantable medical device according to  claim 1 , wherein the expandable support frame is cut from a piece of tubing. 
   
   
       12 . The implantable medical device according to  claim 1 , wherein the expandable support frame is formed of one of a metal, a natural material, a synthetic material, a polymer, and a composite material. 
   
   
       13 . The implantable medical device according to  claim 1 , wherein the expandable support frame is formed of one of stainless steel, Nitinol and cobalt chromium. 
   
   
       14 . The implantable medical device according to  claim 1 , wherein the expandable support frame is formed of a resorbable material. 
   
   
       15 . The implantable medical device according to  claim 1 , wherein the graft member comprises a natural material. 
   
   
       16 . The implantable medical device according to  claim 1 , wherein the graft member comprises a bioremodellable material. 
   
   
       17 . The implantable medical device according to  claim 16 , wherein the bioremodellable material comprises an extracellular matrix material. 
   
   
       18 . The implantable medical device according to  claim 16 , wherein the bioremodellable material comprises small intestine submucosa. 
   
   
       19 . The implantable medical device according to  claim 1 , wherein the graft member comprises a synthetic material. 
   
   
       20 . The implantable medical device according to  claim 1 , wherein the graft member comprises first and second leaflets that define an opening. 
   
   
       21 . The implantable medical device according to  claim 1 , wherein the surface of the expandable support frame has first and second sides and all barbs of the first and second series of barbs are disposed on the first side. 
   
   
       22 . The implantable medical device according to  claim 1 , wherein the surface of the expandable support frame has first and second sides;
 wherein at least one barb of the first series of barbs is disposed on the first side; and   wherein at least one barb of the second series of barbs is disposed on the second side.   
   
   
       23 . The implantable medical device according to  claim 1 , wherein at least one barb is integrally formed by the expandable support frame. 
   
   
       24 . The implantable medical device according to  claim 1 , wherein at least one barb comprises a separate member attached to the expandable support frame. 
   
   
       25 . An implantable medical device according to  claim 1 , wherein the graft member defines a valve for regulating fluid flow through the implantable medical device. 
   
   
       26 . An implantable medical device, comprising:
 an expandable support frame having a first end, a second end, a surface, and a plurality of struts interconnected by bends;   first and second opposing barbs disposed at the first end;   third and fourth opposing barbs disposed at the second end;   a graft member attached to the support frame;   wherein each of the barbs extends away from the surface of the expandable support frame and through the graft member.   
   
   
       27 . An implantable medical device, comprising:
 an expandable support frame having a first end, a second end, a surface, and a plurality of struts interconnected by bends;   first and second barbs disposed on a first strut of the plurality of struts and extending away from the surface in opposing directions;   a graft member having an edge in contact with at least a portion of the surface of the first strut; and   an attachment element placed across the first strut and through the graft member;   wherein the attachment element is disposed between the first and second barbs.