US2010069390A1PendingUtilityA1

Method of treatment of attention deficit/hyperactivity disorder (ADHD)

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Assignee: SUPERNUS PHARMACEUTICALS INCPriority: Sep 5, 2008Filed: Sep 4, 2009Published: Mar 18, 2010
Est. expirySep 5, 2028(~2.2 yrs left)· nominal 20-yr term from priority
A61K 31/00A61P 25/24A61K 31/5375A61P 25/22A61P 25/00
79
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Claims

Abstract

The invention comprises a method for treatment of ADHD or ADHD-related disorders by a pharmaceutical agent exhibiting combined serotonergic or noradrenergic reuptake transporters and monoamine receptor activity.

Claims

exact text as granted — not AI-modified
1 . A method for treatment of ADHD in a human subject in need thereof comprising administering to the subject a therapeutically effective amount of a formulation of viloxazine. 
   
   
       2 . The method of  claim 1 , wherein the therapeutically effective amount is from about 10 to about 600 mg a day. 
   
   
       3 . The method of  claim 1 , wherein the human subject is a human child. 
   
   
       4 . The method of  claim 2 , which provides an improved adverse effect profile. 
   
   
       5 . A method for treatment of ADHD in a human subject in need thereof comprising administering to said subject a therapeutically effective amount of a pharmaceutical agent exhibiting 5HT1B and/or 5HT7 antagonistic activity. 
   
   
       6 . A method for treatment of ADHD in a human subject in need thereof comprising administering to said subject a therapeutically effective amount of a pharmaceutical agent exhibiting combined noradrenergic reuptake inhibitory activity and a 5HT1B or 5HT7 antagonistic activity. 
   
   
       7 . A method for treatment of ADHD in a human subject in need thereof comprising administering to said subject a therapeutically effective amount of a pharmaceutical agent exhibiting combined noradrenergic reuptake inhibitory activity and α 4 /β 2  and/or α7 antagonistic activity. 
   
   
       8 . A method for treatment of ADHD in a human subject in need thereof comprising administering to said subject a therapeutically effective amount of a pharmaceutical agent exhibiting combined 5HT1B and/or 5HT7 antagonistic activity and α 4 /β 2  and/or α7 antagonistic activity.

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