US2010080793A1PendingUtilityA1

DcR3 polypeptide, A TNFR homolog

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Assignee: GENENTECH INCPriority: Sep 18, 1997Filed: Oct 14, 2008Published: Apr 1, 2010
Est. expirySep 18, 2017(expired)· nominal 20-yr term from priority
A61K 38/00C07K 14/70578A01K 2217/05C07K 14/70575C07K 16/2875C12N 2799/026C07K 2317/73A61P 43/00A61P 35/02A61P 35/00C07K 16/2878C07K 2319/00A01K 67/0275
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Claims

Abstract

A TNFR homolog, identified as DcR 3 , is provided. Nucleic acid molecules encoding DcR 3 , chimeric molecules and antibodies to DcR 3 are also provided.

Claims

exact text as granted — not AI-modified
1 - 54 . (canceled) 
     
     
         55 . An article of manufacture, comprising a container and a composition contained within said container, wherein the composition includes DcR3 polypeptide or DcR3 antibodies. 
     
     
         56 . The article of manufacture of  claim 55  further comprising instructions for using the DcR3 polypeptide or DcR3 antibodies in vivo or ex vivo. 
     
     
         57 - 64 . (canceled) 
     
     
         65 . A method of inhibiting a T-cell mediated immune response in a mammal, comprising exposing mammalian cells to DcR3 polypeptide or a chimeric molecule comprising DcR3 polypeptide. 
     
     
         66 . (canceled)

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