US2010087669A1PendingUtilityA1

Novel phenylboronic acid compounds and intermediates and processes for the preparation thereof

Assignee: GALDERMA RES & DEVPriority: Dec 18, 2003Filed: Dec 10, 2009Published: Apr 8, 2010
Est. expiryDec 18, 2023(expired)· nominal 20-yr term from priority
C07C 69/76C07F 5/025C07C 39/15C07C 33/20C07C 43/23C07C 401/00
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Claims

Abstract

Vitamin D derivatives, notably non-steroidal vitamin D derivatives, are prepared from novel disubstituted phenylboronic acid compounds having the formula (I): and also from the novel intermediates having the formulae (1), (2), (3) and (10):

Claims

exact text as granted — not AI-modified
1 . A compound having the following structural formula (1): 
     
       
         
         
             
             
         
       
     
   
   
       2 . A compound having the following structural formula (2): 
     
       
         
         
             
             
         
       
     
     in which:
 R 5  is an alkyl radical having from1 to 4 carbon atoms. 
 
   
   
       3 . A compound having the following structural formula (3): 
     
       
         
         
             
             
         
       
     
     in which
 R1 is a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, and 
 R2 and R3, which may be identical or different, are each an alkyl radical having from 1 to 4 carbon atoms. 
 
   
   
       4 . A compound having the following structural formula (10): 
     
       
         
         
             
             
         
       
     
     in which:
 R1 is a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, 
 R2 and R3, which may be identical or different, are each an alkyl radical having from 1 to 4 carbon atoms, and 
 R′ 1  is an alkyl radical having from 1 to 4 carbon atoms.

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