US2010094014A1PendingUtilityA1

Excitatory amino acid receptor antagonists

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Assignee: MARTINEZ-PEREZ JOSE ANTONIOPriority: Jan 5, 2001Filed: Oct 6, 2009Published: Apr 15, 2010
Est. expiryJan 5, 2021(expired)· nominal 20-yr term from priority
Inventors:Jose Antonio Martinez-PerezThomas M. Wilson
C07D 217/26C07D 401/12C07D 409/14C07D 401/14C07D 417/14
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Claims

Abstract

The present invention provides novel compounds of Formula (I) and Formula (I(a)), or the pharmaceutically acceptable salts thereof; methods for treating neurological disorders and neurodegenerative diseases, particularly pain and migraine, comprising administering a compound of Formula (I) or Formula (I(a)); and processes for preparing compounds of Formula (I) or Formula (I(a)).

Claims

exact text as granted — not AI-modified
1 - 47 . (canceled) 
   
   
       48 . A compound of the formula 
     
       
         
         
             
             
         
       
       wherein Pg represents methoxycarbonyl or t-butoxycarbonyl. 
     
   
   
       49 . The compound according to  claim 48  that is (3S,4aS,6S,8aR)6-[3-chloro-2-(1(2)H-tetrazol-5-yl)-phenoxy]-2-tert-butoxycarbonyl-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid. 
   
   
       50 . The compound according to  claim 48  that is (3S,4aS,6S,8aR)6-[3-chloro-2-(1(2)H-tetrazol-5-yl)-phenoxy]-2-methoxycarbonyl-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid.

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