Over-coated product including tableted center and medicament

Abstract

Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a tableted center. The tableted center is defined by compressible excipients. By chewing the product, the medicament or agent is released from the product within the buccal cavity.

1 . A product comprising a medicament comprising:
 a compressed center comprising at least one compressible saccharide or sugar alcohol; and   a coating comprising a medicament that surrounds the compressed center, the coating comprising at least 50% by weight of the product.   
   
   
       2 . The product of  claim 1 , wherein the medicament is selected from the group consisting of analgesics, muscle relaxants, antibiotics, antivirals, stimulants, antihistamines, decongestants, anti-inflammatories, antacids, psychotherapeutic agents, insulin, vitamins, minerals, nutraceuticals, nutritional supplements, cardiovascular agents, and combinations thereof. 
   
   
       3 . The product of  claim 1 , wherein the coating includes a taste masking agent. 
   
   
       4 . The product of  claim 3 , wherein the taste masking agent is selected from the group consisting of zinc gluconate, ethyl maltol, glycine, acesulfame-k, aspartame, saccharin, fructose, xylitol, isomalt, maltitol, spray dried licorice root, glycerrhizine, sodium gluconate, glucono delta-lactone, ethyl vanillin, dextrose, sucralose, vanillin, ethyl maltol, and combinations thereof. 
   
   
       5 . The product of  claim 3 , wherein the taste masking agent comprises approximately 30% to about 99% by weight of the coating. 
   
   
       6 . The product of  claim 1 , wherein the coating includes approximately 0.1% to about 5% by weight of a high-intensity sweetener selected from the group consisting of aspartame, sucralose, saccharine, acesulfame-k, and combinations thereof. 
   
   
       7 . The product of  claim 1 , wherein the compressed center includes dextrose. 
   
   
       8 . The product of  claim 1 , wherein the coating does not have a shellac layer. 
   
   
       9 . A product comprising a medicament comprising:
 a compressed center comprising at least one saccharide or sugar alcohol; and   a coating comprising a medicament that surrounds the center, the coating comprising at least 50% by weight of the product.   
   
   
       10 . The product of  claim 9 , wherein the medicament is selected from the group consisting of analgesics, muscle relaxants, antibiotics, antivirals, stimulants, antihistamines, decongestants, anti-inflammatories, antacids, psychotherapeutic agents, insulin, vitamins, minerals, nutraceuticals, nutritional supplements, cardiovascular agents, and combinations thereof. 
   
   
       11 . The product of  claim 9 , wherein the coating comprising a taste masking agent. 
   
   
       12 . The product of  claim 11 , wherein the taste masking agent is selected from the group consisting of zinc gluconate, ethyl maltol, glycine, acesulfame-k, aspartame, saccharin, fructose, xylitol, isomalt, maltitol, spray dried licorice root, glycerrhizine, sodium gluconate, glucono delta-lactone, ethyl vanillin, dextrose, sucralose, vanillin, ethyl maltol, and combinations thereof. 
   
   
       13 . The product of  claim 11 , wherein the taste masking agent comprises approximately 30% to about 99% by weight of the coating. 
   
   
       14 . The product of  claim 9 , wherein the coating comprising approximately 0.1% to about 5% by weight of a high-intensity sweetener selected from the group consisting of aspartame, sucralose, saccharine, acesulfame-k, and combinations thereof. 
   
   
       15 . The product of  claim 9 , wherein the center includes dextrose. 
   
   
       16 . The product of  claim 9 , wherein the coating does not have a shellac layer. 
   
   
       17 . A product including a medicament that has acceptable organoleptic properties comprising:
 a compressed center that is defined by at least one excipient; and   a coating that at least substantially surrounds the center and comprising a medicament, the coating comprising at least 50% of the product by weight.   
   
   
       18 . The product of  claim 17 , wherein the medicament is selected from the group consisting of analgesics, muscle relaxants, antibiotics, antivirals, stimulants, antihistamines, decongestants, anti-inflammatories, antacids, psychotherapeutic agents, insulin, vitamins, minerals, nutraceuticals, nutritional supplements, cardiovascular agents, and combinations thereof. 
   
   
       19 . The product of  claim 17 , wherein the excipient is selected from the group consisting of saccharides, sugar alcohols, and combinations thereof. 
   
   
       20 . The product of  claim 17 , wherein a taste masking agent comprises approximately 30% to about 99% by weight of the coating. 
   
   
       21 . The product of  claim 17 , wherein the coating compromises approximately 0.1% to about 5% by weight of a high-intensity sweetener selected from the group consisting of aspartame, sucralose, saccharine, acesulfame-k, and combinations thereof.