US2010120842A1PendingUtilityA1
Neurogenesis by muscarinic receptor modulation
Est. expiryAug 26, 2025(expired)· nominal 20-yr term from priority
Inventors:Carrolee BarlowTodd CarterKym I. LorrainJammieson PiresAndrew MorseDana GitnickKai TreunerAlex Broadhead
A61P 43/00A61P 25/24A61K 31/55A61P 25/08A61K 31/00A61P 25/00A61P 25/32A61K 31/473A61P 25/18A61K 31/445A61K 45/06A61P 25/30A61K 31/325A61K 31/66A61P 25/28A61P 25/20A61K 31/4745A61K 31/403A61P 27/02A61P 25/22A61P 25/36
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Abstract
The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on muscarinic receptor modulation, such as via inhibition of acetylcholine esterase (AChE) activity, alone or in combination with another neurogenic agent to stimulate or activate the formation of new nerve cells.
Claims
exact text as granted — not AI-modified1 . A method of treating a nervous system disorder related to a psychiatric condition, in a subject or patient in need thereof, said method comprising administering a composition consisting essentially of sabcomeline and an S SRI, wherein the composition is effective to treat the disorder.
2 . The method of claim 1 , wherein said psychiatric condition is anxiety.
3 . The method of claim 1 , wherein the SSRI is fluoxetine.Cited by (0)
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