Preservative system for cosmetic formulations

Abstract

Disclosed is a novel method for preserving cosmetic/personal care formulations through a two component preservative system, said system comprising (a) Component I which functions to eliminate the existing microbial contamination load in a natural cosmetic formulation base through an optimized pasteurization method that avoids deep freezing; and (b) Component II that includes the step of adding synergistic blends of fractionated essential oils, extracts and isolated compounds to the pre-pasteurized cosmetic base obtained through the method of component I, wherein the synergistic blends sustain the effects of pasteurization through anti-microbial and anti-oxidant effects, said anti-oxidant effects enhancing further the anti-microbial effects by virtue of inhibiting lipid per oxidation that facilitates the undue proliferation of microbe.

1 . A method for preserving cosmetic/personal care formulations, said method involving a two component preservative system wherein,
 (a) Component I includes an optimized pasteurization method for reducing the existing microbial contamination load of cosmetic base and comprises the steps of:
 i. Dispensing 10 g of the natural cream base comprising naturally occurring microbial contamination into a sterile test tube; 
 ii. Assessing the pre-pasteurization microbial load; 
 iii. Placing the contaminated cosmetic base in a water bath at 63° C. for 30 minutes; and 
   iv. Removing the cosmetic base the water bath and allowing to gradually cool at room temperature, avoiding the conventional step of deep freezing; and   (b) Component II includes the step of adding synergistic blends of fractionated essential oils, extracts and isolated compounds to the pre-pasteurized cosmetic base obtained through the method of component I, wherein the blends sustain the effects of pasteurization through anti-microbial and anti-oxidant effects.   
   
   
       2 . A two-component preservative system for cosmetic/personal care formulations, said system comprising:
 (a) Component I that includes an optimized pasteurization method for reducing the existing microbial contamination load of cosmetic base comprising the steps of:   1. Dispensing 10 g of the natural cream base comprising naturally occurring microbial contamination into a sterile test tube;   2. Assessing the pre-pasteurization microbial load;   3. Placing the contaminated cosmetic base in a water bath at 63° C. for 30 minutes; and   4. Removing the cosmetic base the water bath and allowing to gradually cool at room temperature, avoiding the conventional step of deep freezing; and   (b) Component II that includes the step of adding synergistic blends of fractionated essential oils, extracts and isolated compounds to the pre-pasteurized cosmetic base obtained through the method of component I, wherein the blends sustain the effects of pasteurization through anti-microbial and anti-oxidant effects.   
   
   
       3 . Optimally preserved cosmetic compositions, said compositions preserved by a two-component system comprising:
 (a) Component I that includes an optimized pasteurization method for reducing the existing microbial load (contamination) of cosmetic base through the steps of:   1. Dispensing 10 g of the natural cream base comprising naturally occurring microbial contamination into a sterile test tube;   2. Assessing the pre-pasteurization microbial load;   3. Placing the contaminated cosmetic base in a water bath at 63° C. for 30 minutes; and   4. Removing the cosmetic base the water bath and allowing to gradually cool at room temperature; and   (c) Component II that includes the step of adding synergistic blends of fractionated essential oils, extracts and isolated compounds to the pre-pasteurized cosmetic base obtained through the method of component I, wherein the blends sustain the effects of pasteurization through anti-microbial and anti-oxidant effects.   
   
   
       4 . The synergistic blends of fractionated essential oils, extracts and isolated compounds according to any one of the  claim 1 ,  2 , or  3 , in which the said fractionated essential oils include fractions selected from the group consisting of Cinnamaldehyde; Thymol, Eugenol, Citral, Monolaurin, Garcinol, and extract of  Magnolia officinalis  comprising magnolol and honokiol. 
   
   
       5 . The synergistic blends of fractionated essential oils, extracts and isolated compounds according to  claim 4 , said blend comprising 22% w/w of cinnamaldehyde, 14%-15% w/w of Thymol, 15% w/w of Eugenol, 17% w/w to 18% w/w of Citral, 28% to 29% of monolaurin and 3% w/w of garcinol. 
   
   
       6 . The synergistic blends of fractionated essential oils, extracts and isolated compounds according to  claim 4 , said blend comprising 17% to 18% w/w of cinnamaldehyde, 11% to 12% w/w of Thymol, 12% w/w of Eugenol, 14% w/w of Citral and 45% Monolaurin. 
   
   
       7 . The synergistic blends of fractionated essential oils, extracts and isolated compounds according to  claim 4 , said blend comprising 61% w/w of Thymol, 38% w/w of Monolaurin and 1% w/w of isolated magnolol obtained from the extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       8 . The synergistic blends of fractionated essential oils, extracts and isolated compounds according to  claim 4 , said blends comprising 19% w/w of the blend Thymol, 20% to 22% w/w of the blend Eugenol, 23% to 24% w/w of the blend Citral and 37% to 38% Monolaurin. 
   
   
       9 . Cosmetic formulations according to  claim 3  comprising fractionated essential oils, extracts and isolated compounds selected from the group consisting of Cinnamaldehyde; Thymol, Eugenol, Citral, Monolaurin, Garcinol, and extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       10 . Cosmetic formulation according to  claim 3 , said formulation comprising synergistic anti-microbial and anti-oxidant blends of fractionated essential oils, extracts and isolated compounds including 22% w/w of cinnamaldehyde (assay 90-95%), 14%-15% w/w of Thymol (Assay 95%-98%), 15% w/w of Eugenol (Assay 95% to 99%), 17% to 18% w/w of Citral (Assay 85% to 90%), 28% to 29% of monolaurin and 3% w/w of garcinol (Assay 97%). 
   
   
       11 . Cosmetic formulation according to  claim 3 , said formulation comprising synergistic anti-microbial and anti-oxidant blends of fractionated essential oils, extracts and isolated compounds including 17% to 18% w/w of cinnamaldehyde (assay 90-95%), 11% to 12% w/w of Thymol (Assay 95%-98%), 12% w/w of Eugenol (Assay 95% to 99%), 14% w/w of Citral (Assay 85% to 90%) and 45% Monolaurin (Assay 90%). 
   
   
       12 . Cosmetic formulation according to  claim 3 , said formulation comprising synergistic anti-microbial and anti-oxidant blends of fractionated essential oils, extracts and isolated compounds including 61% w/w of Thymol (Assay 95%-98%), 38% w/w of Monolaurin (Assay 90%) and 1% w/w of isolated magnolol obtained the supercritical fluid extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       13 . Cosmetic formulation according to  claim 3 , said formulation comprising synergistic anti-microbial and anti-oxidant blends of fractionated essential oils, extracts and isolated compounds including 19% w/w of the blend Thymol (Assay 95%-98%), 20% to 22% w/w of the blend Eugenol (assay 95% to 99%), 23% to 24% w/w of the blend Citral (Assay 85% to 90%) and 37% to 38% Monolaurin (Assay 90%). 
   
   
       14 . Anti-microbial formulations according to  claim 4  wherein the compositions comprise fractionated essential oils, extracts and isolated compounds selected from the group consisting of Cinnamaldehyde (90-95%); Thymol (95-98%), Eugenol (95-99%), Citral (85-90%), Monolaurin (Assay-90%), Garcinol (Assay 97%), and extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       15 . Anti-microbial formulations according to  claim 4 , said formulation comprises blends of fractionated essential oils, extracts and isolated compounds consisting of 22% w/w of cinnamaldehyde (assay 90-95%), 14%-15% w/w of Thymol (Assay 95%-98%), 15% w/w of Eugenol (Assay 95% to 99%), 17% to 18% w/w of Citral (Assay 85% to 90%), 28% to 29% of monolaurin and 3% w/w of garcinol (Assay 97%). 
   
   
       16 . Anti-microbial formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds consisting of 17% to 18% w/w of cinnamaldehyde (assay 90-95%), 11% to 12% w/w of Thymol (Assay 95%-98%), 12% w/w of Eugenol (Assay 95% to 99%), 14% w/w of Citral (Assay 85% to 90%) and 45% Monolaurin (Assay 90%). 
   
   
       17 . Anti-microbial formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds consisting of 61% w/w of Thymol (Assay 95%-98%), 38% w/w of Monolaurin (Assay-90%) and 1% w/w of isolated magnolol obtained from the supercritical fluid extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       18 . Anti-microbial formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds consisting of 19% w/w of the blend Thymol (Assay 95%-98%), 20% to 22% w/w of the blend Eugenol (assay 95% to 99%), 23% to 24% w/w of the blend Citral (Assay 85% to 90%) and 37% to 38% Monolaurin (Assay 90%). 
   
   
       19 . Anti-oxidant formulations according to  claim 4 , wherein the material includes fractionated essential oils, extracts and isolated compounds selected from the group consisting of Cinnamaldehyde (90-95%); Thymol (95-98%), Eugenol (95-99%), Citral (85-90%), Monolaurin (Assay-90%), Garcinol (Assay-97%), and supercritical fluid extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       20 . Anti-oxidant formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds including 22% w/w of cinnamaldehyde (assay 90-95%), 14%-15% w/w of Thymol (Assay 95%-98%), 15% w/w of Eugenol (Assay 95% to 99%), 17% to 18% w/w of Citral (Assay 85% to 90%), 28% to 29% of monolaurin and 3% w/w of garcinol (Assay 97%). 
   
   
       21 . Anti-oxidant formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds 17% to 18% w/w of cinnamaldehyde (assay 90-95%), 11% to 12% w/w of Thymol (Assay 95%-98%), 12% w/w of Eugenol (Assay 95% to 99%), 14% w/w of Citral (Assay 85% to 90%) and 45% Monolaurin (Assay-90%). 
   
   
       22 . Anti-oxidant formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds including 61% w/w of Thymol (Assay 95%-98%), 38% w/w of Monolaurin (Assay-90%) and 1% w/w of isolated magnolol obtained the supercritical fluid extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       23 . Anti-oxidant formulations according to  claim 4 , said formulation comprising blends of fractionated essential oils, extracts and isolated compounds consisting of 19% w/w of the blend Thymol (Assay 95%-98%), 20% to 22% w/w of the blend Eugenol (assay 95% to 99%), 23% to 24% w/w of the blend Citral (Assay 85% to 90%) and 37% to 38% Monolaurin (Assay 90%). 
   
   
       24 . Natural plant material based preservative formulations as in one of  claim 1  or  2  in which the said formulation comprises blends of fractionated essential oils, extracts and isolated compounds selected from the group consisting of Cinnamaldehyde (90-95%); Thymol (95-98%), Eugenol (95-99%), Citral (85-90%), Monolaurin (Assay 90%), Garcinol (Assay 97%), and extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       25 . Natural plant material based preservative formulations as in one of  claim 1  or  2  in which the said formulation comprises blends of fractionated essential oils, extracts and isolated compounds including 22% w/w of cinnamaldehyde (assay 90-95%), 14%-15% w/w of Thymol (Assay 95%-98%), 15% w/w of Eugenol (Assay 95% to 99%), 17% to 18% w/w of Citral (Assay 85% to 90%), 28% to 29% of monolaurin and 3% w/w of garcinol (Assay 97%). 
   
   
       26 . Natural plant material based preservative formulations as in one of  claim 1  or  2  in which the said formulation comprises blends of fractionated essential oils, extracts and isolated compounds including 17% to 18% w/w of cinnamaldehyde (assay 90-95%), 11% to 12% w/w of Thymol (Assay 95%-98%), 12% w/w of Eugenol (Assay 95% to 99%), 14% w/w of Citral (Assay 85% to 90%) and 45% Monolaurin (Assay-90%). 
   
   
       27 . Natural plant material based preservative formulations as in one of  claim 1  or  2  in which the said formulation comprises blends of fractionated essential oils, extracts and isolated compounds including 61% w/w of Thymol (Assay 95%-98%), 38% w/w of Monolaurin (Assay-90%) and 1% w/w of isolated magnolol obtained from the supercritical fluid extracts of  Magnolia officinalis  comprising Magnolol and honokiol. 
   
   
       28 . Natural plant material based preservative formulations as in one of  claim 1  or  2  in which the said formulation comprises blends of fractionated essential oils, extracts and isolated compounds including 19% w/w of the blend Thymol (Assay 95%-98%), 20% to 22% w/w of the blend Eugenol (assay 95% to 99%), 23% to 24% w/w of the blend Citral (Assay 85% to 90%) and 37% to 38% Monolaurin (Assay 90%). 
   
   
       29 . Synergistic blends of fractionated essential oils, extracts and isolated compounds according to any one of the  claims 1 ,  2 ,  3 , in which said blends are shelf stable with no effects of rancidity.