US2010168254A1PendingUtilityA1
Hydrogel composition for the treatment of dermatological disorders
Est. expiryDec 23, 2028(~2.4 yrs left)· nominal 20-yr term from priority
A61P 29/00A61P 17/00A61P 17/10A61P 17/08A61K 8/8147A61K 47/10A61K 8/345A61Q 19/00A61K 47/14A61K 9/06A61K 8/553A61K 9/0014A61K 47/38A61K 47/24A61K 47/12A61K 8/042
52
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Cited by
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Claims
Abstract
The present patent application is related to a hydrogel composition which is essentially free of active drugs for the manufacture of a product for the treatment of dermatological disorders, especially perioral dermatitis, acne or seborrheic dermatitis.
Claims
exact text as granted — not AI-modified1 . A composition in form of a hydrogel which is essentially free of active pharmaceuticals.
2 . A composition in form of a hydrogel which is essentially free of active pharmaceuticals according to claim 1 , wherein the hydrogel contains at least a surfactant, propylene glycol, lecithin and a lipid.
3 . A composition in form of a hydrogel which is essentially free of active pharmaceuticals according to claim 1 , wherein the hydrogel contains
(i) 5-15% propylene glycol (ii) 0-2% polyacrylic acid (iii) 0.5-3% lecithin (iv) 0.5-3% medium chain triglycerides or macrogol-glycerol hydroxystearate.
4 . A composition in form of a hydrogel which is essentially free of active pharmaceuticals according to claim 1 , wherein the hydrogel is consisting of one of the following compositions:
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4
5
6
7
8
9
Benzoic acid
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
Sodium edentate
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
Sodium hydroxide
0.2
0.1
0.2
2
—
0.1
0.1
0.2
0.2
Polyacrylic acid
1.0
—
1.0
1.0
—
0.5
—
1.0
—
Acrylic acid
—
0.5
—
—
—
—
0.3
—
—
copolymer
Hydroxyethylcellulose
—
—
—
—
—
—
—
—
0.5
Xanthan gum
—
—
—
—
0.8
0.5
0.3
—
—
Propylene glycol
12.0
8.0
12.0
6.0
12.0
12.0
12.0
8.0
8.0
Glycerol
—
—
—
6.0
—
—
—
8.0
—
Polysorbate 80
1.5
1.5
1.5
—
1.5
1.5
1.5
1.5
1.5
Macrogol-glycerol-
—
—
1.5
—
—
—
—
—
hydroxystearate
Medium chain
1.0
2.0
1.0
1.0
1.0
3.0
3.0
1.0
1.0
triglycerides
Dimeticone
—
—
1.0
—
—
—
—
—
—
Liquid paraffin
—
—
—
—
1.0
—
—
—
—
Lecithin
1.0
2.0
1.0
1.0
1.0
1.5
1.0
1.0
1.0
Purified water to
100.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
5 . A method for the treatment of dermatological disorders, especially perioral dermatitis, acne or seborrheic dermatitis, comprising administering a hydrogel which is essentially free of active pharmaceuticals.
6 . A method according to claim 5 , wherein the hydrogel contains at least a surfactant, propylene glycol, lecithin and a lipid.
7 . A method for the treatment of perioral dermatitis, acne or seborrheic dermatitis according to claim 5 , wherein the hydrogel contains
(i) 5-15% propylene glycol (ii) 0-2% polyacrylic acid (iii) 0.5-3% lecithin (iv) 0.5-3% medium chain triglycerides or macrogol-glycerol hydroxystearate.
8 . A method for the treatment of perioral dermatitis, acne or seborrheic dermatitis comprising administering the composition of claim 4 .
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9
Benzoic acid
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
Sodium edentate
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
0.1
Sodium hydroxide
0.2
0.1
0.2
2
—
0.1
0.1
0.2
0.2
Polyacrylic acid
1.0
—
1.0
1.0
—
0.5
—
1.0
—
Acrylic acid
—
0.5
—
—
—
—
0.3
—
—
copolymer
Hydroxyethylcellulose
—
—
—
—
—
—
—
—
0.5
Xanthan gum
—
—
—
—
0.8
0.5
0.3
—
—
Propylene glycol
12.0
8.0
12.0
6.0
12.0
12.0
12.0
8.0
8.0
Glycerol
—
—
—
6.0
—
—
—
8.0
—
Polysorbate 80
1.5
1.5
1.5
—
1.5
1.5
1.5
1.5
1.5
Macrogol-glycerol-
—
—
1.5
—
—
—
—
—
hydroxystearate
Medium chain
1.0
2.0
1.0
1.0
1.0
3.0
3.0
1.0
1.0
triglycerides
Dimeticone
—
—
1.0
—
—
—
—
—
—
Liquid paraffin
—
—
—
—
1.0
—
—
—
—
Lecithin
1.0
2.0
1.0
1.0
1.0
1.5
1.0
1.0
1.0
Purified water to
100.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
9 . A method of treatment for humans suffering from dermatological disorders, such as perioral dermatitis, seborrhoic dermatitis or acne, by topical administration of a hydrogel composition according to claim 1 .
10 . A method of claim 6 for the treatment of perioral dermatitis, acne or seborrheic dermatitis.
11 . A method of claim 7 for the treatment of perioral dermatitis, acne or seborrheic dermatitis.Cited by (0)
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