Therapy Triggered by Predication of Disordered Breathing

Abstract

An approach to providing disordered breathing therapy includes providing therapy based on a prediction of disordered breathing. One or more patient conditions are detected and used to predict disordered breathing. Therapy is delivered to mitigate the predicted disordered breathing. The disordered breathing therapy may be adapted to enhance therapy efficacy and/or to reduce the impact of the therapy to the patient.

1 . A method of providing disordered breathing therapy to a patient, comprising:
 detecting via a detector system one or more conditions associated with disordered breathing of a patient;   predicting disordered breathing based on the one or more detected conditions using at least a first disordered breathing prediction criteria set;   estimating an accuracy of the first disordered breathing prediction criteria set;   adapting a therapy for the patient to mitigate the predicted disordered breathing; and   delivering the adapted therapy to the patient via a therapy delivery system, wherein at least one of predicting, adapting, and delivering is performed at least in part implantably.   
   
   
       2 . The method of  claim 1 , wherein each of predicting, adapting, and delivering is performed at least in part implantably. 
   
   
       3 . The method of  claim 1 , further comprising:
 using a first group of the one or more detected conditions for predicting disordered breathing; and   using a second group of the detected conditions for adapting the therapy to mitigate the predicted disordered breathing.   
   
   
       4 . The method of  claim 3 , wherein the one or more detected conditions comprises any combination of a physiological condition and a contextual condition. 
   
   
       5 . The method of  claim 3 , wherein the second group of the detected conditions comprises one or more of: a condition used to assess an impact of the therapy on the patient a condition used to assess therapy efficacy, a condition associated with sleep quality, a condition associated with patient comfort, a condition used to assess respiration quality, a cardiovascular system condition, a respiratory system condition, a nervous system condition, a blood chemistry condition, and a muscle system condition. 
   
   
       6 . The method of  claim 1 , wherein adapting the therapy comprises adapting the therapy based on one or more of patient therapy interactions and detection of one or more episodes of disordered breathing. 
   
   
       7 . The method of  claim 6 , wherein the detection of the one or more episodes of disordered breathing comprises detecting any combination of a severity, a duration, and a frequency of the one or more detected episodes of disordered breathing. 
   
   
       8 . The method of  claim 1 , wherein adapting the therapy comprises adapting the therapy to perform any combination of terminating and preventing the predicted disordered breathing. 
   
   
       9 . The method of  claim 1 , wherein adapting the therapy comprises adapting a cardiac pacing therapy. 
   
   
       10 . The method of  claim 9 , wherein adapting the cardiac pacing therapy comprises adapting any combination of atrial pacing therapy, ventricular pacing therapy, multi-chamber pacing therapy. 
   
   
       11 . The method of  claim 9 , wherein adapting the cardiac pacing therapy comprises any combination of adapting the cardiac pacing therapy at a rate above an intrinsic rate, adapting the cardiac pacing therapy at a rate above a normally programmed pacing rate, switching pacing sites, and switching pacing modes. 
   
   
       12 . A medical device, comprising:
 a detector system configured to detect one or more conditions associated with disordered breathing of a patient;   a prediction engine coupled to the detector system and configured to:
 predict disordered breathing based on the detected conditions using at least a first disordered breathing prediction criteria set; 
 estimate an accuracy of the first disordered breathing prediction criteria set; and 
 adapt a therapy for the patient to mitigate the predicted disordered breathing; and 
   a therapy delivery system coupled to the prediction engine and the detector system and configured to deliver the adapted therapy to the patient, wherein the prediction engine includes an implantable component.   
   
   
       13 . The medical device of  claim 12 , wherein one or both of the therapy delivery system and the detector system include implantable components. 
   
   
       14 . The medical device of  claim 12 , wherein the prediction engine is further configured to:
 use a first group of the one or more detected conditions for predicting disordered breathing; and   use a second group of the detected conditions for adapting the therapy to mitigate the predicted disordered breathing.   
   
   
       15 . The medical device of  claim 14 , wherein the one or more conditions comprise any combination of a physiological condition and a contextual condition. 
   
   
       16 . The medical device of  claim 14 , wherein the second group of the detected conditions comprises one or more of: a condition used to assess an impact of the therapy on the patient a condition used to assess therapy efficacy, a condition associated with sleep quality, a condition associated with patient comfort, a condition used to assess respiration quality, a cardiovascular system condition, a respiratory system condition, a nervous system condition, a blood chemistry condition, and a muscle system condition. 
   
   
       17 . The medical device of  claim 12 , wherein adapting the therapy comprises adapting the therapy based on one or more of patient therapy interactions and detection of one or more episodes of disordered breathing. 
   
   
       18 . The medical device of  claim 12 , wherein adapting the therapy comprises adapting the therapy to perform any combination of terminating and preventing the predicted disordered breathing. 
   
   
       19 . The medical device of  claim 12 , wherein adapting the therapy comprises adapting a cardiac pacing therapy. 
   
   
       20 . The medical device of  claim 12 , wherein the prediction engine is configured to perform real-time prediction of the disordered breathing.