Closure devices, systems, and methods

Abstract

The present disclosure includes vessel closure devices, systems, and methods. A closure device configured to close an opening in a body lumen may include an elongate member having a distal end and a proximal end. An anchor member may be disposed on the elongate member proximate the distal end of the elongate member. A cap member may also be disposed on the elongate member a distance from the distal end of the elongate member. The anchor member and the cap member cooperate to close the opening in the body lumen.

1 . A closure device configured to close an opening in a body lumen, the closure device comprising:
 an elongate member having a distal end and a proximal end;   an anchor member disposed on the elongate member proximate the distal end of the elongate member; and   a cap member disposed on the elongate member a distance from the distal end of the elongate member, wherein the anchor member and the cap member are positioned to close the opening in the body lumen.   
   
   
       2 . The closure device of  claim 1 , wherein the elongate member comprises a metal or plastic shaft. 
   
   
       3 . The closure device of  claim 1 , wherein the elongate member comprises a suture. 
   
   
       4 . The closure device of  claim 3 , further comprising a second elongate member disposed substantially in parallel with the first elongate member, the second elongate member comprising a suture. 
   
   
       5 . The closure device of  claim 1 , wherein the elongate member comprises a hollow shaft and the closure device further comprises a plug configured to be inserted into the hollow shaft to expand the hollow shaft. 
   
   
       6 . The closure device of  claim 1 , wherein the elongate member comprises one or more projections disposed along the length thereof. 
   
   
       7 . The closure device of  claim 6 , wherein the one or more projections are chosen from a group comprising teeth, barbs, and ridges. 
   
   
       8 . The closure device of  claim 6 , wherein the one or more projections are configured to permit movement by the cap member in a distal direction and resist movement by the cap member in a proximal direction. 
   
   
       9 . The closure device of  claim 1 , wherein the cap member is slidably disposed on the elongate member. 
   
   
       10 . The closure device of  claim 1 , wherein the anchor member or cap member comprises a biodegradable material. 
   
   
       11 . The closure device of  claim 1 , wherein the anchor member or cap member is disc shaped. 
   
   
       12 . The closure device of  claim 1 , wherein the anchor member or cap member has a varying thickness. 
   
   
       13 . The closure device of  claim 1 , wherein the elongate member comprises a bioabsorbable monofilament. 
   
   
       14 . The closure device of  claim 1 , wherein the anchor member is coupled to the elongate member proximate a knot. 
   
   
       15 . The closure device of  claim 1 , further comprising a cleat, collet, or knot disposed on the elongate member proximal of the cap member. 
   
   
       16 . A closure system comprising:
 a generally tubular outer member having a distal opening and a proximal opening;   a generally tubular intermediate member disposed at least partially within the outer member; and   a closure device disposed at least partially within the outer member, the closure device comprising:
 an elongate member having a distal end and a proximal end, the elongate member being disposed at least partially through the intermediate member; 
 an anchor member disposed on the elongate member proximate the distal end of the elongate member, the anchor member being further disposed within the outer member distal of the intermediate member; and 
 a cap member disposed on the elongate member a distance from the distal end of the elongate member, the cap member being further disposed within the outer member proximal of the anchor member. 
   
   
   
       17 . The closure system of  claim 16 , wherein the outer member comprises a non-rigid catheter. 
   
   
       18 . The closure system of  claim 16 , further comprising a generally tubular inner member disposed at least partially within the outer member and/or intermediate member. 
   
   
       19 . The closure system of  claim 18 , wherein the inner member comprises a guidewire lumen, fluid marker port, and/or flow back lumen. 
   
   
       20 . The closure system of  claim 18 , wherein the inner member and the intermediate member are integrated together into a single component. 
   
   
       21 . The closure system of  claim 16 , wherein the intermediate member comprises a pusher tube. 
   
   
       22 . The closure system of  claim 16 , wherein the intermediate member is movable relative to the outer member. 
   
   
       23 . The closure system of  claim 22 , wherein the distal movement of the intermediate member relative to the outer member is limited to the movement necessary deploy the anchor member from the distal opening of the outer member. 
   
   
       24 . The closure system of  claim 16 , further comprising a collagen or polyethylene glycol plug configured to at least partially obstruct a tissue tract proximate a body lumen opening. 
   
   
       25 . A method of closing an opening in a lumen wall, the method comprising:
 advancing the distal end of a closure system over a guidewire into a body lumen, the closure system comprising:
 a generally tubular outer member having a distal opening and a proximal opening; 
 a generally tubular intermediate member disposed at least partially within the outer member; and 
 a closure device disposed at least partially within the outer member, the closure device comprising:
 an elongate member having a distal end and a proximal end, the elongate member being disposed at least partially through the intermediate member; 
 an anchor member disposed on the elongate member proximate the distal end of the elongate member, the anchor member being further disposed within the outer member distal of the intermediate member; and 
 a cap member disposed on the elongate member a distance from the distal end of the elongate member, the cap member being further disposed within the outer member proximal of the anchor member. 
 
   deploying the anchor member into the lumen;   tensioning the elongate member to engage the anchor member with a distal surface of the lumen wall; and   deploying the cap member and advancing the cap member in a distal direction along the elongate member to engage a proximal surface of the lumen wall.   
   
   
       26 . The method of  claim 25 , further comprising positioning a knot, collet, or cleat on the elongate member proximal of the cap member. 
   
   
       27 . The method of  claim 25 , further comprising retracting the outer member in a proximal direction to deploy the cap member. 
   
   
       28 . The method of  claim 25 , wherein the closure system further comprises a generally tubular inner member disposed at least partially within the intermediate member.