Antiperspirant Active Compositions Having SEC Chromatogram Exhibiting High SEC Peak 4 Intensity

Abstract

An antiperspirant active composition comprising an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, exhibiting a SEC chromatogram having a SEC Peak 4 to Peak 3 intensity ratio of at least 7 and a Peak 4 intensity greater than a Peak 5 intensity in aqueous solution. The composition can optionally include zirconium. Also, methods of making.

1 . An antiperspirant active composition comprising an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, exhibiting a SEC chromatogram having a SEC Peak 4 to Peak 3 intensity ratio of at least 7 and a Peak 4 intensity greater than a Peak 5 intensity in aqueous solution. 
   
   
       2 . The antiperspirant active of  claim 1 , wherein the composition further comprises zirconium. 
   
   
       3 . The antiperspirant active of  claim 1 , wherein the aluminum salt is buffer free and has an OH to Al ratio of about 2:1 to about 2.6:1. 
   
   
       4 . The antiperspirant active of  claim 1  further comprising a buffer, wherein a molar ratio of buffer to aluminum is about 0.1:1 to about 3:1. 
   
   
       5 . The antiperspirant active of  claim 4 , wherein the buffer is at least one buffer chosen from an amino acid, glycine, and betaine. 
   
   
       6 . The antiperspirant active of  claim 1 , wherein the zirconium is present and a molar ratio of aluminum to zirconium is about 5:1 to about 10:1. 
   
   
       7 . The antiperspirant active composition of  claim 1 , wherein the composition has a SEC Peak 4 area of at least 50% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       8 . The antiperspirant active composition of  claim 1 , wherein the composition has a SEC Peak 4 area of 95 to 100% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       9 . The antiperspirant active composition of  claim 1 , wherein the composition has a SEC Peak 3 area of less than about 10% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       10 . The antiperspirant active composition of  claim 1 , wherein the composition has no SEC Peak 3 area in the SEC chromatogram. 
   
   
       11 . The antiperspirant active composition of  claim 1 , wherein the composition has a SEC Peak 5 area of less than about 30% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       12 . The antiperspirant active composition of  claim 1 , wherein the composition has no SEC Peak 5 area in the SEC chromatogram. 
   
   
       13 . The antiperspirant active composition of  claim 1 , wherein the composition has a SEC Peak 1 area of less than about 10% and a SEC Peak 2 area of less than about 10% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       14 . The antiperspirant active composition of  claim 1 , wherein the composition has a SEC Peak 4 area of 95 to 100%, no SEC Peak 3 area, and no SEC Peak 5 area of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       15 . A method of making an antiperspirant active composition comprising:
 I) heating an aqueous solution containing an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, optionally with a buffer agent, at a temperature of about 50° C. to about 95° C. to reflux for a period of time of about 1 hour to about 5 hours to obtain an aluminum salt solution:   II) adding an aqueous solution of an inorganic base to obtain an aluminum salt solution having an OH:Al molar ratio of about 2:1 to about 2.6:1 to obtain a pH adjusted aluminum salt solution having a pH of about 2 to about 5; and   III) optionally adding an aqueous solution containing a zirconium compound to the pH adjusted aluminum salt solution to thereby obtain an aluminum-zirconium salt solution having a molar ratio of aluminum to zirconium of about 5:1 to about 10:1.   
   
   
       16 . The method of  claim 15 , wherein the buffer is present in a molar ratio of buffer to aluminum is about 0.1:1 to about 3:1. 
   
   
       17 . The method of  claim 15 , wherein the buffer agent is at least one buffer chosen from an amino acid, glycine, and betaine. 
   
   
       18 . The method of  claim 15 , wherein the inorganic base includes at least one member chosen from metal hydroxides, calcium hydroxide, strontium hydroxide, barium hydroxide, metal oxides, calcium oxide, strontium oxide, and barium oxide. 
   
   
       19 . The method of  claim 15 , wherein the aluminum chloride compound is chosen from aluminum trichloride, aluminum chlorohexahydrate, and aluminum dichlorohydrate. 
   
   
       20 . The method of  claim 15 , wherein the composition further comprises zirconium. 
   
   
       21 . The method of  claim 20 , wherein the zirconium is ZrOCl 2 .8H 2 O. 
   
   
       22 . The method of clam  15 , wherein the antiperspirant active composition exhibits a SEC chromatogram having a SEC Peak 4 to Peak 3 intensity ratio of at least 7 and a Peak 4 intensity greater than a Peak 5 intensity in aqueous solution. 
   
   
       23 . The method of  claim 22 , wherein the antiperspirant active composition has a SEC Peak 4 area of at least 50% of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       24 . The method of  claim 22 , wherein the antiperspirant active composition has a SEC Peak 4 area of 95 to 100% of the total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       25 . The method of  claim 22 , wherein the antiperspirant active composition has a SEC Peak 3 area of less than about 10% of the total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram. 
   
   
       26 . The method of  claim 22 , wherein the antiperspirant active composition has no SEC Peak 3 area. 
   
   
       27 . The method of  claim 22 , wherein the antiperspirant active composition has a SEC Peak 5 area of less than about 30% of the total area of Peaks 1, 2, 3, 4, 5, and 6. 
   
   
       28 . The method of  claim 22 , wherein the antiperspirant active composition has no SEC Peak 5 area. 
   
   
       29 . The method of  claim 22 , wherein the antiperspirant active composition has a SEC Peak 1 area of less than about 10% and a SEC Peak 2 area of less than about 10% of the total area of Peaks 1, 2, 3, 4, 5, and 6. 
   
   
       30 . The method of  claim 22 , wherein the composition has a SEC Peak 4 area of 95 to 100%, no SEC Peak 3 area, and no SEC Peak 5 area of a total area of Peaks 1, 2, 3, 4, 5, and 6 in the SEC chromatogram.