N-oxides of n-phenyl-2-pyramidine-amine derivatives

Abstract

The invention relates to N-phenyl-2-pyrimidine-amine derivatives derivatives in which at least one nitrogen atom carries an oxygen atom to form the corresponding N-oxides, to processes for the preparation thereof, to pharmaceutical compositions comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.

1 . A compound which is 4-[(methyl-1-piperazinyl)-methyl]-N-[4-methyl-3-[[4-(1-oxido-3-pyridinyl)-2-pyrinidinyl]-amino]-phenyl]-benzamide, or a pharmaceutically acceptable salt thereof. 
   
   
       2 . A pharmaceutical composition comprising a compound according to  claim 1  together with a pharmaceutically acceptable carrier. 
   
   
       3 . A method of treating a warm-blooded animal suffering from a proliferative disorder, which comprises administering to the warm-blooded animal a dose effective against the disorder of a compound according to  claim 1 .