Composition and method for the oxidative consumption of salivary biomolecules

Abstract

The composition and method for the use of stabilized chlorine dioxide as an antimicrobial agent against oral microorganisms for the treatment and prevention of halitosis and prevention of oral diseases through its oxidative consumption and inactivation of volatile sulfur compounds and their amino acid precursors is disclosed. Preferred concentrations of stabilized chlorine dioxide in this invention are in the range of 0.005% to 2.0% (w/v).

1 . A composition for oxidentively consuming salivary biomolecules, said composition comprising a solution of stabilized chlorine dioxide having a concentration in the range of about 0.05% to about 2.0% (w/v) to oxidatively consume pyruvate, methionine, trimethylamine, tyrosine, glycine, creatine, 3-D-hydroxybutyrate, salivary taurine, lactate, and lysine. 
     
     
         2 . A composition for reducing halitosis and oral disease present in the oral cavity, said composition comprising stabilized chlorine dioxide solution having a concentration in the range of about 0.05% to about 2.0% (w/v) for oxidatively consuming volatile sulphur compounds and their amino acid precursors present in the oral cavity to produce chlorine dioxide. 
     
     
         3 . The composition as set forth in  claim 2  wherein the concentration of stabilized chlorine dioxide is approximately 0.1% (w/v). 
     
     
         4 . The composition as set forth in  claim 3  wherein the concentration of stabilized chlorine dioxide is approximately 0.4% (w/v). 
     
     
         5 . Use of a composition of stabilized chlorine dioxide solution having a concentration in the range of about 0.005% to about 2.0% (w/v) for oxidatively consuming salivary molecules to reduce the presence of volatile sulphur compounds and oral diseases present in the oral cavity. 
     
     
         6 . The use as set forth in  claim 5  wherein the salivary molecules are selected from the group consisting of pyruvate, methionine, trimethylamine, tyrosine, glycine, creatine, hydroxybutyrate, salivary taurine, lactate and lysine. 
     
     
         7 . A method for treating the oral cavity, said method comprising the steps of:
 a) applying stabilized chlorine dioxide in a range of about 0.005% to about 2.0% (w/v) to the oral cavity;   b) oxidatively consuming salivary molecules selected from the group consisting of pyruvate, methionine, trimethylamine, tryosine, glycine, creatine, 3-D-hydroxybutyrate, salivary taurine, lactate and lysine;   c) reducing the presence of halitosis; and   d) urging reduction of the oral diseases present in the oral cavity.