US2010240904A1PendingUtilityA1

Processes for the preparation of n-(2-acetyl-4,6-dimethylphenyl)-3--2-thiophenecarboxamide

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Assignee: PFIZERPriority: Aug 4, 2006Filed: Jun 3, 2010Published: Sep 23, 2010
Est. expiryAug 4, 2026(expired)· nominal 20-yr term from priority
Inventors:John Reichwein
A61P 9/10A61P 43/00A61P 9/12A61P 9/00A61P 29/00A61P 11/08A61P 13/12C07D 333/40C07D 333/38C07D 513/04C07D 413/12A61P 11/06C07D 333/34
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Claims

Abstract

Provided are processes for the preparation of N-(2-acetyl-4,6-dimethylphenyl)-3-{[(3,4 dimethyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxamide, a compound useful for the treatment of endothelin-mediated disorders.

Claims

exact text as granted — not AI-modified
1 - 62 . (canceled) 
     
     
         63 . A compound of Formula (II): 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable derivative thereof. 
     
     
         64 . A compound of Formula (IV): 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable derivative thereof. 
     
     
         65 . A compound of Formula (VI): 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable derivative thereof.

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