Biological active coating components, coatings, and coated surfaces

Abstract

Disclosed herein are novel coatings and paints comprising a biomolecule composition, wherein the biomolecule composition comprises a phosphoric triester hydrolase. Also disclosed herein are methods of detoxification of a surface contaminated with an organophosphorus compound by contacting the surface with such a coating or paint. Also disclosed herein are novel coating and paint components derived from microorganisms.

1 - 256 . (canceled) 
     
     
         257 . A method of detoxification of a surface contaminated with an organophosphorus compound, comprising the steps of: contacting a surface contaminated with an organophosphorous compound with a coating comprising a biomolecule composition, wherein the biomolecule composition comprises a phosphoric triester hydrolase. 
     
     
         258 . The method of  claim 257 , wherein said organophosphorus compound comprises a chemical warfare agent. 
     
     
         259 . The method of  claim 258 , wherein the chemical warfare agent comprises a persistent agent. 
     
     
         260 . The method of  claim 258 , wherein the chemical warfare agent comprises a G-agent, a V agent, or a combination thereof. 
     
     
         261 . The method of  claim 260 , wherein said G-agent comprises soman, sarin, cyclosarin, tabun, or a combination of any thereof. 
     
     
         262 . The method of  claim 260 , wherein said V-agent comprises VX, Russian VX, or a combination thereof. 
     
     
         263 . The method of  claim 257 , wherein said organophosphorus compound comprises a pesticide. 
     
     
         264 . The method of  claim 263 , wherein the pesticide comprises a persistent organophosphorous compound. 
     
     
         265 . The method of claim  28   263 , wherein the pesticide comprises bromophosethyl, chiorpyrifos, chlorfenvinphos, chiorothiophos, chiorpyrifos-methyl, coumaphos, crotoxyphos, crufomate, cyanophos, diazinon, dichlofenthion, dichiorvos, dursban, EPN, ethoprop, ethyl-parathion, etrimifos, famphur, fensulfothion, fenthion, fenthrothion, isofenphos, jodfenphos, leptophos-oxon, malathion, methyl-parathion, mevinphos, paraoxon, parathion, parathion-methyl, pirimiphos-ethyl, pirimiphos-methyl, pyrazophos, quinaiphos, ronnel, sulfopros, sulfotepp, trichioronate, or a combination thereof. 
     
     
         266 . The method of  claim 257 , wherein the method further comprises the step of contacting the surface with a caustic agent; a decontaminating foam, a combination of baking condition heat and carbon dioxide, or a combination thereof. 
     
     
         267 . A method of detoxification of an organophosphorus compound, comprising the steps of: contacting an organophosphorous compound with a coating comprising a biomolecule composition, wherein the biomolecule composition comprises a phosphoric triester hydrolase. 
     
     
         268 . A method of reducing the concentration of an organophosphorus compound upon a surface, comprising the steps of: applying to the surface a coating comprising a biomolecule composition, wherein the biomolecule composition comprises a phosphoric triester hydrolase, and contacting the surface with an organophosphorus compound. 
     
     
         269 - 321 . (canceled) 
     
     
         322 . A method of detoxification of a surface contaminated with an organophosphorus compound, comprising the steps of: coating a surface with a coating comprising a biomolecule composition, wherein the biomolecule composition comprises a phosphoric triester hydrolase. 
     
     
         323 . The method of  claim 322  wherein the surface is coated prior to contamination with an organophosphorous compound. 
     
     
         324 . The method of  claim 322 , wherein the organophosphorus compound comprises a chemical warfare agent. 
     
     
         325 . The method of  claim 324 , wherein the chemical warfare agent comprises a persistent agent. 
     
     
         326 . The method of  claim 324 , wherein the chemical warfare agent comprises a Gagent, a V agent, or a combination thereof. 
     
     
         327 . The method of  claim 326 , wherein said G-agent comprises soman, sarin, cyclosarin, tabun, or a combination of any thereof. 
     
     
         328 . The method of  claim 326 , wherein said V-agent comprises VX, Russian VX, or a combination thereof. 
     
     
         329 . The method of  claim 322 , wherein said organophosphorus compound comprises a pesticide. 
     
     
         330 . The method of  claim 329 , wherein the pesticide comprises a persistent organophosphorous compound. 
     
     
         331 . The method of  claim 329 , wherein the pesticide comprises bromophos-ethyl, chiorpyrifos, chlorfenvinphos, chiorothiophos, chiorpyrifos-methyl, coumaphos, crotoxyphos, crufomate, cyanophos, diazinon, dichiofenthion, dichiorvos, dursban, EPN, ethoprop, ethyl-parathion, etrimifos, famphur, fensulfothion, fenthion, fenthrothion, isofenphos, jodfenphos, leptophos-oxon, malathion, methyl-parathion, mevinphos, paraoxon, parathion, parathion-methyl, pirimiphos-ethyl, pirimiphos-methyl, pyrazophos, quinaiphos, ronnel, sulfopros, sulfotepp, trichloronate, or a combination thereof. 
     
     
         332 . The method of  claim 322 , wherein the method further comprises the step of contacting the surface with a caustic agent; a decontaminating foam, a combination of baking condition heat and carbon dioxide, or a combination thereof.