Preparation of therapeutic foam

Abstract

Closed pouch comprising a wall defining an enclosed space containing carbon dioxide, and a pair of syringes contained within the enclosed space. The syringes are connected together by a syringe connector, and of the syringes contains a gas or gas mixture other than air, while the other contains a foamable liquid. Breakage of the syringe, connector and pumping of the syringes produces a foam useful in the treatment of varicose veins.

1 - 12 . (canceled) 
     
     
         13 . A closed pouch comprising:
 a wall defining an enclosed space containing carbon dioxide; and   a pair of syringes contained within said enclosed space, said syringes being connected together by a syringe connector, one of said syringes containing a gas or gas mixture other than air and the other of said syringes containing a foamable liquid.   
     
     
         14 . A pouch as claimed in  claim 13  wherein said wall comprises a metalized plastics laminate. 
     
     
         15 . A pouch as claimed in  claim 13  wherein the gas or gas mixture consists substantially of oxygen, carbon dioxide or a mixture thereof. 
     
     
         16 . A vessel as claimed in  claim 13  wherein the foamable liquid is a sclerosant liquid solution. 
     
     
         17 . A vessel as claimed in  claim 16  wherein the foamable liquid is a 1% solution of polidocanol. 
     
     
         18 . A pouch as claimed in  claim 13 , wherein the wall is hermetically sealed. 
     
     
         19 . A pouch as claimed in  claim 13  wherein the contents of the pouch are sterile. 
     
     
         20 . A pouch as claimed in  claim 13  wherein the pressure of the carbon dioxide in the enclosed space is 1.1 bar absolute. 
     
     
         21 . A closed pouch comprising:
 a wall defining an enclosed space containing carbon dioxide; and   a double plunger syringe contained within said enclosed space, said syringe containing a gas or gas mixture other than air and a foamable liquid.   
     
     
         22 . Method of producing a foam using a pouch as claimed in  claim 13 , comprising breaking said syringe connector and pumping the syringes to produce a foam. 
     
     
         23 . Method as claimed in  claim 22  wherein said pumping is performed manually or by using a machine.