US2010261271A1PendingUtilityA1
Regulation of endogenous gene expression in cells using zinc finger proteins
Est. expiryJan 12, 2019(expired)· nominal 20-yr term from priority
A61P 7/00A61P 3/06A61P 43/00A61P 9/00A61P 37/00A61P 9/10A61P 7/06A61P 31/00A61P 31/04A61P 31/18A61P 33/02A61P 25/28A61P 31/12A61P 35/00A61P 31/10A61P 27/02A61P 29/00A61P 21/04A61P 21/00C07K 14/52A01K 67/0275A61P 17/06C12N 15/85C07K 2319/71A01K 2217/05C12N 15/63C07K 2319/81C12Q 1/6897A61K 48/00G01N 33/5091C12N 2830/85C07K 2319/00C07K 14/47C12N 15/8216C12N 2830/002A61P 11/00A61P 19/02A61K 48/005C12N 15/67C12N 2830/005C12Q 1/66C12N 2830/008
65
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
Claims
exact text as granted — not AI-modified1 . A cell comprising an engineered zinc finger protein bound to a target site in an endogenous cellular gene in its normal genomic and chromatin context, wherein the zinc finger protein comprises at least one non-naturally occurring recognition helix region that is engineered to bind to the target site in the endogenous cellular gene.
2 . The cell of claim 1 , wherein the protein further comprises a transcriptional regulatory domain.Cited by (0)
No later patents cite this yet.
References (0)
No backward citations on record.