Infusion container with multiple chambers

Abstract

The present invention has an object to provide an infusion container with multiple chambers, where the peel strength of the boundary portion between one and another of multiple medicament chambers is stabilized irrespective of the construction material and structure of the film. The present invention provides an infusion container 10 with multiple chambers, which is formed from a thermoplastic resin film and has a plurality of medicament chambers 11 and 12 for housing medicaments, wherein the medicaments chambers 11 and 12 are liquid-tightly sealed by a peelable weak seal part 15, the weak seal part 15 is formed to have a plurality of melt-bonding parts different in the melt-bonding strength, the strong melt-bonding part having a largest melt-bonding strength among these melt-bonding parts is dispersed and distributed in the weak seal part 15, and the total occupied area of the strong melt-bonding part is less than 25% of the area of the weak seal part 15.

1 . A method for producing an infusion container with multiple chambers, which has a plurality of medicament chambers for housing medicaments and in which said medicaments chambers are liquid-tightly sealed from each other by a peelable weak seal part, said method comprising:
 a weak seal step of sandwiching superposed two thermoplastic resin films from both surface sides using two heat seal bars to form a weak seal part having a plurality of melt-bonding parts different in the melt-bonding strength,   wherein said weak seal step is performed such that the total occupied area of the strong melt-bonding part having a largest melt-bonding strength among said melt-bonding parts and being dispersed and distributed in said weak seal part is less than 25% of the area of said weak seal part.   
     
     
         2 . The method for producing an infusion container with multiple chambers as claimed in  claim 1 , wherein a seal edge is formed on the seal surface of at least one of said heat seal bars. 
     
     
         3 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein said seal edge comprises a plurality of projected streaks formed almost in parallel and each having a width of 1 mm or less and/or a plurality of projected planes each having an area of 1 mm 2  or less. 
     
     
         4 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein a seal edge is formed on the seal surface of one heat seal bar and the seal surface of another heat seal bar is formed planarly. 
     
     
         5 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein a seal edge is formed on the seal surface of both heat seal bars. 
     
     
         6 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein the average distance between respective seal edges is 1.0 mm or more. 
     
     
         7 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein the edge angle of each seal edge is 120° or less. 
     
     
         8 . The method for producing an infusion container with multiple chambers as claimed in  claim 1 , wherein said method comprises a strong seal step of sandwiching at least a part of the peripheral edge of said infusion container with multiple chambers from both surface sides by heat seal bars to liquid-tightly close said peripheral edge part and said strong seal step and said weak seal step are simultaneously performed. 
     
     
         9 . The method for producing an infusion container with multiple chambers as claimed in  claim 1 , wherein the weak seal step is performed such that the elevation rate of the opening strength in the weak seal part with respect to the heat seal temperature is 1,000 N/° C. or less. 
     
     
         10 . The method for producing an infusion container with multiple chambers as claimed in  claim 3 , wherein a seal edge is formed on the seal surface of one heat seal bar and the seal surface of another heat seal bar is formed planarly. 
     
     
         11 . The method for producing an infusion container with multiple chambers as claimed in  claim 3 , wherein a seal edge is formed on the seal surface of both heat seal bars. 
     
     
         12 . The method for producing an infusion container with multiple chambers as claimed in  claim 3 , wherein the average distance between respective seal edges is 1.0 mm or more. 
     
     
         13 . The method for producing an infusion container with multiple chambers as claimed in  claim 4 , wherein the average distance between respective seal edges is 1.0 mm or more. 
     
     
         14 . The method for producing an infusion container with multiple chambers as claimed in  claim 5 , wherein the average distance between respective seal edges is 1.0 mm or more. 
     
     
         15 . The method for producing an infusion container with multiple chambers as claimed in  claim 3 , wherein the edge angle of each seal edge is 120° or less. 
     
     
         16 . The method for producing an infusion container with multiple chambers as claimed in  claim 4 , wherein the edge angle of each seal edge is 120° or less. 
     
     
         17 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein said method comprises a strong seal step of sandwiching at least a part of the peripheral edge of said infusion container with multiple chambers from both surface sides by heat seal bars to liquid-tightly close said peripheral edge part and said strong seal step and said weak seal step are simultaneously performed. 
     
     
         18 . The method for producing an infusion container with multiple chambers as claimed in  claim 3 , wherein said method comprises a strong seal step of sandwiching at least a part of the peripheral edge of said infusion container with multiple chambers from both surface sides by heat seal bars to liquid-tightly close said peripheral edge part and said strong seal step and said weak seal step are simultaneously performed. 
     
     
         19 . The method for producing an infusion container with multiple chambers as claimed in  claim 2 , wherein the weak seal step is performed such that the elevation rate of the opening strength in the weak seal part with respect to the heat seal temperature is 1,000 N/° C. or less. 
     
     
         20 . The method for producing an infusion container with multiple chambers as claimed in  claim 3 , wherein the weak seal step is performed such that the elevation rate of the opening strength in the weak seal part with respect to the heat seal temperature is 1,000 N/° C. or less.