US2010305323A1PendingUtilityA1

Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof

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Assignee: SMOLENSKAYA VALERIYA NPriority: Mar 29, 2007Filed: Mar 28, 2008Published: Dec 2, 2010
Est. expiryMar 29, 2027(~0.7 yrs left)· nominal 20-yr term from priority
Inventors:Valeriya SmolenskayaKadum A. Al ShareffiJulio PerezSyed M. ShahThomas A. Boyd
A61P 43/00A61P 39/02A61P 25/04A61P 17/04A61P 1/08A61P 17/00A61P 1/00A61P 1/10A61P 1/14A61P 13/02A61K 31/485C07D 489/08C07D 491/08C07D 489/04
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Claims

Abstract

The present invention provides a new forms of (R)—N-methylnaltrexone, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.

Claims

exact text as granted — not AI-modified
1 - 51 . (canceled) 
     
     
         52 . Substantially pure amorphous Compound 1: 
       
         
           
           
               
               
           
         
         where the compound is in the (R) configuration with respect to the nitrogen.

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