US2011027399A1PendingUtilityA1

Antiviral Agent and Antiviral Composition

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Assignee: UNIV HIROSHIMAPriority: Mar 31, 2008Filed: Mar 31, 2009Published: Feb 3, 2011
Est. expiryMar 31, 2028(~1.7 yrs left)· nominal 20-yr term from priority
A61P 31/20A61P 31/12A61P 3/00A61P 31/02A61P 31/14A61K 31/7024A61K 31/194A61K 31/60A61K 45/06A61K 31/353A61K 31/235A61K 31/19A61P 17/00A61K 36/44A01N 65/08A61K 36/742A61K 31/05Y02A50/30
52
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Claims

Abstract

An antiviral agent is provided which has an excellent effect on a non-enveloped virus and which is highly safe to the human body, and an antiviral composition which comprises the antiviral agent and which is useful for disinfection of the virus or prevention of infection of the virus. The antiviral agent comprises as an active ingredient an extract from a plant of the genus Diospyros containing tannin, a catechin, wattle tannin, pentagalloyl glucose, coffee tannin, an alkyl gallate (excluding that in the above-described persimmon extract), pyrogallol, or an organic acid and/or a salt thereof (excluding that in the above-described persimmon extract). The antiviral composition is characterized by comprising at least the antiviral agent and an alcohol, a surfactant, a microbicide, a humectant, or a cosmetic fat and oil, and preferably further comprises citric acid and/or a salt thereof or vitamin C.

Claims

exact text as granted — not AI-modified
29 . An antiviral agent against a non-enveloped virus comprising, as an active ingredient, a treated persimmon extract obtained by heating a squeezed juice or an extract from a fruit of a plant of the genus  Diospyros  containing tannin or treating the squeezed juice or the extract with an alcohol in order to inactive an enzyme contained therein and derived from the plant of the genus  Diospyros , wherein the non-enveloped virus is a non-enveloped virus belonging to the genus  Betanodavirus, Aquavirnavirus, Ranavirus, Enterovirus, Mastadenovirus, Vesivirus , or  Rotavirus.    
     
     
         30 . The antiviral agent according to  claim 29 , wherein the treated persimmon extract contains at least condensed tannin. 
     
     
         31 . The antiviral agent according to  claim 29 , wherein the persimmon extract is obtained from Diospyros kaki. 
     
     
         32 . The antiviral agent according to  claim 29 , further comprising, as an active ingredient, at least one selected from the group consisting of a catechin, wattle tannin, pentagalloyl glucose, coffee tannin, an alkyl gallate (excluding that in the treated persimmon extract), pyrogallol, and an organic acid and/or a salt thereof (excluding that in the treated persimmon extract). 
     
     
         33 . The antiviral agent according to  claim 29 , wherein the non-enveloped virus is nervous necrosis virus, infectious pancreatic necrosis virus, red seabream iridovius, Coxsackie virus, adenovirus, feline calicivirus, or rotavirus. 
     
     
         34 . An antiviral alcohol preparation comprising at least the antiviral agent according to  claim 29  and an alcohol. 
     
     
         35 . An antiviral washing composition comprising at least the antiviral agent according to  claim 29 . 
     
     
         36 . An antiviral disinfectant composition comprising at least the antiviral agent according to  claim 29  and an antimicrobial agent (excluding ethanol, an organic acid, and a salt thereof). 
     
     
         37 . The antiviral composition according to  claim 34 , wherein the antiviral agent contains the treated persimmon extract at a ratio of 0.01% to 5% by weight (in terms of solid content) based on the total composition. 
     
     
         38 . The antiviral composition according to  claim 34 , further comprising vitamin C. 
     
     
         39 . The antiviral agent according to  claim 30 , wherein the persimmon extract is obtained from  Diospyros kaki.    
     
     
         40 . The antiviral agent according to  claim 30 , further comprising, as an active ingredient, at least one selected from the group consisting of a catechin, wattle tannin, pentagalloyl glucose, coffee tannin, an alkyl gallate (excluding that in the treated persimmon extract), pyrogallol, and an organic acid and/or a salt thereof (excluding that in the treated persimmon extract). 
     
     
         41 . The antiviral agent according to  claim 31 , further comprising, as an active ingredient, at least one selected from the group consisting of a catechin, wattle tannin, pentagalloyl glucose, coffee tannin, an alkyl gallate (excluding that in the treated persimmon extract), pyrogallol, and an organic acid and/or a salt thereof (excluding that in the treated persimmon extract). 
     
     
         42 . An antiviral alcohol preparation comprising at least the antiviral agent according to  claim 30  and an alcohol. 
     
     
         43 . An antiviral alcohol preparation comprising at least the antiviral agent according to  claim 31  and an alcohol. 
     
     
         44 . An antiviral alcohol preparation comprising at least the antiviral agent according to  claim 32  and an alcohol. 
     
     
         45 . An antiviral alcohol preparation comprising at least the antiviral agent according to  claim 33  and an alcohol. 
     
     
         46 . An antiviral washing composition comprising at least the antiviral agent according to  claim 30 . 
     
     
         47 . An antiviral disinfectant composition comprising at least the antiviral agent according to  claim 30  and an antimicrobial agent (excluding ethanol, an organic acid, and a salt thereof). 
     
     
         48 . The antiviral composition according to  claim 35 , wherein the antiviral agent contains the treated persimmon extract at a ratio of 0.01% to 5% by weight (in terms of solid content) based on the total composition.

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