Socs3 expression promoter, drug and food containing the same and method of promoting the expression of socs3

Abstract

A SOCS3 expression promoter includes hyaluronic acid having an average molecular weight of 500,000 or more and/or a salt thereof as an active ingredient.

1 . A SOCS3 expression promoter comprising hyaluronic acid having an average molecular weight of 500,000 or more and/or a salt thereof as an active ingredient. 
     
     
         2 . The SOCS3 expression promoter according to  claim 1 , wherein the hyaluronic acid and/or a salt thereof has an average particle diameter of 50 to 500 micrometers. 
     
     
         3 . A drug comprising the SOCS3 expression promoter according to  claim 1  as an active ingredient. 
     
     
         4 . The drug according to  claim 3 , the drug being orally administered. 
     
     
         5 . A food comprising the SOCS3 expression promoter according to  claim 1 . 
     
     
         6 . A method of promoting expression of SOCS3 in a human or an animal other than a human, the method comprising orally administering hyaluronic acid having an average molecular weight of 500,000 or more and/or a salt thereof to a human or an animal other than a human. 
     
     
         7 . A pleiotrophin expression inhibitor comprising hyaluronic acid having an average molecular weight of 500,000 or more and/or a salt thereof as an active ingredient. 
     
     
         8 . The pleiotrophin expression inhibitor according to  claim 7 , wherein the hyaluronic acid and/or a salt thereof has an average particle diameter of 50 to 500 micrometers. 
     
     
         9 . A drug comprising the pleiotrophin expression inhibitor according to  claim 7  as an active ingredient. 
     
     
         10 . The drug according to  claim 9 , the drug being orally administered. 
     
     
         11 . A food comprising the pleiotrophin expression inhibitor according to  claim 7 . 
     
     
         12 . A method of inhibiting expression of pleiotrophin in a human or an animal other than a human, the method comprising orally administering hyaluronic acid having an average molecular weight of 500,000 or more and/or a salt thereof to a human or an animal other than a human. 
     
     
         13 . The drug according to  claim 3 , the drug being used to treat a knee joint or relieve knee pain. 
     
     
         14 . The food according to  claim 5 , the food being used to treat a knee joint or relieve knee pain. 
     
     
         15 . (canceled) 
     
     
         16 . (canceled) 
     
     
         17 . The drug according to  claim 9 , the drug being used to treat a knee joint or relieve knee pain. 
     
     
         18 . The food according to  claim 11 , the food being used to treat a knee joint or relieve knee pain.