US2011111414A1PendingUtilityA1
Detecting Agent and Therapeutic Agent for Highly Malignant Breast Cancer
Est. expiryDec 14, 2025(expired)· nominal 20-yr term from priority
Inventors:Yasushi NakamuraHironao YasuokaMasahiko TsujimotoRieko GotoZenzaburo TozukaKunio MomiyamaKennichi KakudoTomonori Takami
C07K 16/18A61K 47/6843A61P 35/04A61P 35/00C07K 16/3015C12Q 1/6886C12Q 2600/158A61K 47/6855G01N 33/57515
30
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Claims
Abstract
A detection agent for high malignancy breast cancer includes an antibody against collagen XIV, or a variant or derivative or fragment of the antibody. A therapeutic agent for high malignancy breast cancer includes a conjugate of an anticancer drug and an antibody against that protein, or a variant or derivative or fragment thereof. Accordingly, it is possible to easily and accurately detect and diagnose high malignancy breast cancer.
Claims
exact text as granted — not AI-modified1 . A method for detecting high malignancy breast cancer in a cytological specimen, comprising: preparing a cDNA from a cytological specimen; performing PCR with the cDNA as a template and using a primer pair specific for a DNA encoding collagen XIV; and detecting a resultant PCR product.
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