Occlusive cinching devices and methods of use

Abstract

Methods and devices for blocking orifices and occluding cavities within a patient are provided. The device in one variation comprises first and second tubular members attached to a collapsible sealing element. The device can be placed through an orifice and the collapsible sealing element can be collapsed to seal the orifice. An embolic may be introduced distal to the sealing element to occlude a cavity. The device may incorporate a locking mechanism which can be engaged to lock the sealing element into the collapsed position. The device may incorporate a valve to prevent flow through the tubular members, for example to prevent egress of the embolic from a cavity. The device can be detached to provide a permanent seal of the orifice, and can retain the embolic within the cavity. The device may be used in conjunction with a stent or other retention device to assist the sealing element in maintaining the seal.

1 . An occlusive device, comprising:
 a first tubular member comprising a first distal end and a first lumen;   a second tubular member comprising a second distal end and a second lumen, said second tubular member received within the first lumen of the first tubular member;   a collapsible sealing element adapted to be disposed within a body cavity across a passage thereto, said sealing element having a collapsed shape and an extended shape, said sealing element comprising a first end and a second end, said first end detachably connected to said first tubular member at or near said first distal end, and said second end detachably connected to said second tubular member at or near said second distal end, said extended shape being generally extended longitudinally along the axis of the second tubular member, said collapsed shape being generally collapsed longitudinally along said axis and expanded generally radially outwards therefrom to form a barrier;   said first and second tubular members being longitudinally movable relative to one another to control the movement of the sealing element between the collapsed and extended shapes; and   a valve which seals the second lumen to prevent egress of an embolic therethrough.   
     
     
         2 . The occlusive device of  claim 1 , further comprising a locking mechanism separate from the collapsible sealing element that can be engaged to lock the sealing element in the collapsed shape. 
     
     
         3 . The occlusive device of  claim 2 , wherein the locking mechanism is selected from the group consisting of a friction fit, a latch, an entanglement system, a dimple, a detent, and a locking barb. 
     
     
         4 . The occlusive device of  claim 1 , wherein the sealing element is provided with a protective sheath that can be retracted to release the sealing element. 
     
     
         5 . The occlusive device of  claim 1 , wherein the valve comprises flaps which are collapsed into the second lumen after introduction of the embolic. 
     
     
         6 . The occlusive device of  claim 1 , wherein the valve comprises an annular collapsible seal that collapses to seal the second lumen after detachment from the second tubular member. 
     
     
         7 . The occlusive device of  claim 1 , further comprising a plurality of ports near said second distal end for introducing the embolic. 
     
     
         8 . A method of blocking an orifice within a patient, comprising
 introducing the device of  claim 1  into the patient;   positioning the sealing element to engage the orifice;   manipulating the first and second tubular members to move the sealing element into the collapsed shaped blocking said orifice; and   detaching the sealing element.   
     
     
         9 . An occlusive device, comprising:
 a first tubular member comprising a first distal end and a first lumen;   a second tubular member comprising a second distal end and a second lumen, said second tubular member received within the first lumen of the first tubular member; and   a collapsible sealing element adapted to be disposed within a body cavity across a passage thereto, said sealing element having a collapsed shape and an extended shape, said extended shape being generally extended longitudinally along the axis of the second tubular member, said collapsed shape being generally collapsed longitudinally along said axis and expanded generally radially outwards therefrom to form a barrier,   said sealing element positioned so as to be retained within the first tubular member during delivery of the device, said sealing element comprising a first end and a second end, said first end comprising a deployable engagement system for engaging the first distal end upon retraction of the first tubular member to expose the sealing element and deploy the engagement system, and said second end detachably connected to said second tubular member at or near said second distal end;   said first and second tubular members longitudinally movable relative to one another to control the movement of the sealing element between the extended and collapsed shapes.   
     
     
         10 . The occlusive device of  claim 9 , wherein the sealing element comprises a braided mesh tube. 
     
     
         11 . The occlusive device of  claim 10 , wherein the mesh is selected from the group consisting of a polymer yarn, a polyester yarn, and a metal wire. 
     
     
         12 . The occlusive device of  claim 11 , wherein the metal wire is a nitinol wire. 
     
     
         13 . The occlusive device of  claim 10 , wherein the mesh comprises a radioopaque element. 
     
     
         14 . The occlusive device of  claim 10 , wherein the mesh comprises a combination of different materials.