Mycotoxin-reducing composition

Abstract

A composition comprising an enzyme, a mycotoxin-binding agent and a microorganism capable of taking up a mycotoxin.

1 . A composition comprising an enzyme, a mycotoxin-binding agent and a  saccharomyces  yeast capable of taking up a mycotoxin. 
     
     
         2 . The composition according to  claim 1 , wherein the active agents consist of the enzyme, mycotoxin-binding agent and  saccharomyces  yeast capable of taking up a mycotoxin. 
     
     
         3 . The composition according to  claim 1 , wherein the  saccharomyces  yeast is  Saccharomyces cerevisiae.    
     
     
         4 . The composition according to  claim 1 , wherein the enzyme is an esterase, lipase, protease, oxidase, amino acid oxidase, lactonohydrolase, peroxidase, lactoperoxidase, manganese peroxidase, epoxidase, polysaccharase or dehydrogenase. 
     
     
         5 . The composition according to  claim 1 , wherein the binder comprises a polysaccharide, such as glucomannan, or a bentonite. 
     
     
         6 . The composition according to  claim 1 , wherein the microorganism expresses at least one enzyme selected from among an esterase, lipase, protease, oxidase, amino acid oxidase, lactonohydrolase, peroxidase, lactoperoxidase, manganese peroxidase, epoxidase, polysaccharase, and dehydrogenase. 
     
     
         7 . The composition according to  claim 1 , comprising a further microorganism that expresses at least one enzyme selected from among an esterase, lipase, protease, oxidase, amino acid oxidase, lactonohydrolase, peroxidase, lactoperoxidase, manganese peroxidase, epoxidase, polysaccharase, and dehydrogenase. 
     
     
         8 . The composition according to  claim 1  for application to a foodstuff. 
     
     
         9 . The composition according to  claim 1 , wherein the toxin binder is charged. 
     
     
         10 . A method of reducing the toxicity of a mycotoxin in a foodstuff, comprising the step of contacting the foodstuff with a composition comprising an enzyme, a mycotoxin-binding agent and a  saccharomyces  yeast capable of taking up a mycotoxin. 
     
     
         11 . The method according to  claim 10 , wherein the mycotoxin to be modified is a tricothene. 
     
     
         12 . The method according to  claim 11 , wherein the tricothene mycotoxin to be modified is Deoxynivalenol. 
     
     
         13 . The method according to  claim 10 , wherein the mycotoxin to be modified is Zearalenone, Aflatoxin, Fumonisin, Roquefortin, an ochratoxin or an endophyte toxin. 
     
     
         14 . The method according to  claim 13 , wherein the endophyte is Lolitrem B, sporidesmin or ergovaline. 
     
     
         15 . The method according to  claim 10 , wherein the foodstuff is contacted with the composition prior to consumption by an animal. 
     
     
         16 . The method according to  claim 10 , wherein the foodstuff is contacted with the composition simultaneous with consumption by an animal. 
     
     
         17 . The method according to  claim 10 , wherein the enzyme potentiates the toxin binding to the toxin binder. 
     
     
         18 . A foodstuff comprising a composition comprising an enzyme, a mycotoxin-binding agent and a  saccharomyces  yeast capable of taking up a mycotoxin. 
     
     
         19 - 21 . (canceled) 
     
     
         22 . A method for the treatment of a disease caused by mycotoxin in a human or non-human animal, comprising providing a composition to the human or non-human animal for consumption, wherein the composition comprises an enzyme, a mycotoxin-binding agent and a  saccharomyces  yeast capable of taking up a mycotoxin, and wherein the composition is consumed by the human or non-human animal. 
     
     
         23 . The method according to  claim 22 , wherein a foodstuff comprising the composition is provided to the human or non-human animal, and wherein the foodstuff is consumed by the human or non-human animal. 
     
     
         24 . A method for making a composition, comprising combining an enzyme, a mycotoxin-binding agent and a  saccharomyces  yeast capable of taking up a mycotoxin.