Cosmetic or dermopharmaceutical composition containing pseudoalteromonas ferment extract

Abstract

Cosmetic or dermopharmaceutical compositions containing Pseudoalteromonas ferment extract for the treatment and/or care of the skin, scalp and/or nails, preferably to improve the barrier function of the skin, scalp and/or nails, and specifically for the treatment and/or care of those conditions, disorders and/or pathologies of the skin, scalp and/or nails associated with an alteration in the keratinization process.

1 .- 24 . (canceled) 
     
     
         25 . A method for the treatment and/or care of symptoms associated with keratinization disorders and/or pathologies which comprises the topical or transdermal application on the skin, scalp and/or nails of an effective amount of a cosmetic or dermopharmaceutical composition containing  Pseudoalteromonas  ferment extract. 
     
     
         26 . A method according to  claim 25 , where the keratinization disorders and/or pathologies are selected from the group consisting hyperkeratosis, reactive hyperkeratosis, palmar and plantar hyperkeratosis, calluses or corns, actinic keratosis, non-actinic keratosis, atopical dermatitis, contact eczema, seborrheic dermatitis, dandruff, cradle cap in infants, acne, rosacea, nevus, ichthyosis, psoriasis, parakeratosis, pityriasis, lichen planus, palmoplantar keratoderma, Darier's disease, onychomycosis, dermatomycosis, certain benign tumor proliferations, such as papillomas or warts, keratoacanthoma or seborrheic keratosis, malignant tumor proliferations, keloids and thinning and fragility of the epidermis. 
     
     
         27 . A method according to  claim 25 , where  Pseudoalteromonas  ferment extract is added to compositions by aqueous solution, or solubilized in conventional cosmetically or dermopharmaceutically acceptable solvents selected from the group consisting of ethanol, propanol, isopropanol, propylene glycol, glycerin, butylene glycol, or polyethylene glycol and mixtures thereof. 
     
     
         28 . A method according to  claim 25 , characterized because the cosmetic or dermopharmaceutical composition is added to cosmetic or dermopharmaceutical delivery systems and/or sustained-release systems. 
     
     
         29 . A method according to  claim 28 , where the delivery systems or sustained-release systems are selected from the group consisting of liposomes, mixed liposomes, oleosomes, milliparticles, microparticles, nanoparticles and solid lipid nanoparticles, sponges, cyclodextrins, vesicles, micelles, mixed micelles, millispheres, microspheres, nanospheres, lipospheres, millicapsules, microcapsules, nanocapsules, microemulsions and nanoemulsions. 
     
     
         30 . A method according to  claim 28 , where the cosmetic or dermopharmaceutical delivery systems are selected from the group consisting of water, peanut oil, soybean oil, mineral oil, sesame oil, castor oils, polysorbates, sorbitan esters, sulfate esters, sulfates, betaines, glucosides, maltosides, fatty alcohols, nonoxynols, poloxamers, polyoxyethylenes, polyethylene glycols, dextrose, glycerol, digitonin and mixtures thereof. 
     
     
         31 . A method according to  claim 25 , where the cosmetic or dermopharmaceutical composition is adsorbed on a cosmetically or dermopharmaceutically acceptable organic polymer or solid mineral support selected from the group consisting of talcum, bentonite, silica, starch and maltodextrin. 
     
     
         32 . A method according to  claim 25 , where  Pseudoalteromonas  ferment extract is at a concentration between 0.00000001% and 40% in weight. 
     
     
         33 . A method according to  claim 32 , where  Pseudoalteromonas  ferment extract is at a concentration between 0.00001% and 30% in weight. 
     
     
         34 . A method according to  claim 33 , where  Pseudoalteromonas  ferment extract is at a concentration between 0.0001% and 20% in weight. 
     
     
         35 . A method according to  claim 25 , where the cosmetic or dermopharmaceutical composition is presented as a formulation selected from the group consisting of creams, oil in water emulsions, silicone in water emulsions, water in oil emulsions, water in silicone emulsions, water/oil/water emulsions, water/silicone/water emulsions, oil/water/oil emulsions, silicone/water/silicone emulsions, anhydrous compositions, aqueous dispersions, oils, milks, balsams, foams, lotions, gels, cream gels, hydroalcoholic solutions, hydroglycolic solutions, liniments, sera, soaps, shampoos, conditioners, serums, polysaccharide films, ointments, mousses, pomades, powders, bars, pencils, sprays or aerosols, leave-on or rinse off formulations. 
     
     
         36 . A method according to  claim 25 , where the cosmetic or dermopharmaceutical composition is incorporated into fluid foundations and compact foundations, make-up removal lotions, make-up removal milks, concealers, eye shadow, lipstick, lip protectors, lip glosses, powders, nail enamel, nail enamel removers or cuticle remover lotions. 
     
     
         37 . A method according to  claim 25 , where the cosmetic or dermopharmaceutical composition is incorporated to fabrics, non-woven fabrics or medical devices. 
     
     
         38 . A method according to  claim 37 , where the fabric, non-woven fabric or medical device is selected from the group consisting of bandages, gauzes, shirts, socks, stockings, underwear, girdles, gloves, diapers, sanitary towels, dressings, bedspreads, wipes, hydrogels, adhesive patches, non-adhesive patches, microelectric patches and facial masks. 
     
     
         39 . A method according to  claim 25 , where the cosmetic or dermopharmaceutical composition additionally comprises a cosmetically or dermopharmaceutically effective amount of at least one cosmetic or dermopharmaceutical adjuvant selected from the group consisting of cosmetic or dermopharmaceutical adjuvants that recover and/or maintain the barrier function of the skin, scalp and/or nails, anti-hyperkeratosis agents, comedolytic agents, anti-seborrheic agents, anti-psoriasis agents, epidermal hydrolytic enzymes, alpha-hydroxy acids, beta-hydroxy acids, desquamating agents, exfoliating agents, keratolytic agents, reactive carbonyl species scavengers, agents stimulating or inhibiting melanin synthesis, whitening or depigmenting agents, propigmentation agents, self-tanning agents, anti-aging agents, agents inhibiting NO-synthase, organic solvents, liquid propellants, vitamins, hormones, amino acids, anti-wrinkle agents, skin-relaxing agents, agents capable of reducing or treating bags under the eyes, anti-itching agents, agents for the treatment and/or care of sensitive skin, firming agents, astringent agents, agents stimulating lipolysis, anti-cellulite agents, anti-perspirant agents, calming agents, anti-inflammatory agents, analgesic agents, anesthetic agents, agents acting on cell metabolism, agents to improve the dermal-epidermal junction, humectants, substances that retain moisture, moisturizers, emollients, emulsifying agents, agents stimulating the synthesis of lipids and components of the stratum corneum, agents inhibiting 5α-reductase, agents inhibiting lysyl- and/or prolyl-hydroxylase, antioxidant agents, free radical scavengers and/or agents against atmospheric pollution, anti-glycation agents, antimicrobial agents, fungicidal agents, fungistatic agents, bactericidal agents, bacteriostatic agents, antihistamine agents, antiviral agents, anti-parasitic agents, agents stimulating synthesis of dermal or epidermal macromolecules and/or capable of inhibiting or preventing their degradation, such as, including but not limited to, agents stimulating collagen synthesis, agents stimulating elastin synthesis, agents stimulating decorin synthesis, agents stimulating laminin synthesis, agents stimulating defensin synthesis, agents stimulating chaperone synthesis, agents stimulating sirtuin synthesis, agents stimulating hyaluronic acid synthesis, agents stimulating aquaporin synthesis, agents stimulating fibronectin synthesis, agents inhibiting matrix metalloprotease, agents inhibiting collagen degradation, agents inhibiting elastin degradation, agents inhibiting serine protease such as leukocyte elastase or cathepsin G, agents stimulating fibroblast proliferation, agents stimulating keratinocyte proliferation, agents stimulating adipocyte proliferation, agents regulating keratinocyte differentiation, agents stimulating keratinocyte differentiation, agents stimulating adipocyte differentiation, agents inhibiting acetylcholinesterase, agents inhibiting vascular permeability, venotonic agents, agents stimulating angiogenesis, agents stimulating glycosaminoglycan synthesis, DNA repairing agents, DNA protecting agents, anti-stretch mark agents, agents regulating sebum production, agents stimulating healing, coadjuvant healing agents, reepithelialization agents, cytokine growth factors, agents acting on capillary circulation and/or microcirculation, agents inducing hair growth, agents inhibiting or retarding hair growth, muscle relaxants, pigments or colorants, dyes, gelling polymers, thickeners, softeners, preservatives, stabilizing agents, perfumes, odor absorbents, chelanting agents, plant extracts, essential oils, marine extracts, agents obtained from a biofermentation process, mineral salts, cell extracts and sunscreens, among others and mixtures thereof, as long as they are physically and chemically compatible with the rest of the components of the composition of the present invention. 
     
     
         40 . A method according to  claim 39 , where the cosmetic or dermopharmaceutical adjuvant is of synthetic origin or a plant extract or comes from a biofermentation process. 
     
     
         41 . A method according to  claim 39 , where the cosmetic or dermopharmaceutical adjuvants that recover and/or maintain the barrier function of the skin, scalp and/or nails, humectants, substances that retain moisture, moisturizers and emollients are selected from the group consisting of polyols and derivatives thereof, polyesters and derivatives thereof, panthenol, pyroglutamic acid and salts and derivatives thereof, amino acids, ectoine and derivatives thereof, N-(2-hydroxyethyl)acetamide, N-lauroyl-pyrrolidonecarboxylic acid, N-lauroyl-L-lysine, N-alpha-benzoyl-L-arginine, urea, creatine, alpha-hydroxy acids and beta-hydroxy acids and salts thereof, polyglyceryl acrylate, sugars and polysaccharides, glycosaminoglycans and derivatives thereof, aloe vera, honey, soluble collagen, lecithin and phosphatidylcholine, ceramides, cholesterol and esters thereof, tocopherol and esters thereof, long-chain alcohols, long-chain alcohol esters, fatty acids, polyunsaturated acids, sorbitans, glycerides, sucrose esters, butyleneglycol esters, fatty acid esters, squalene, mink oil, lanolin and derivatives thereof, acetylated lanolin alcohols, silicone derivatives, petrolatum, mineral oil, mineral and synthetic waxes, bees wax, paraffin, and waxes and oils of vegetable origin and mixtures thereof. 
     
     
         42 . A method according to  claim 39 , where the keratolytic agents, exfoliating agents or desquamating agents are selected from the group consisting of hydroxy acids and derivatives thereof, beta-hydroxy acids, alpha-hydroxy acids and salts thereof, polyhydroxy acids, keto acids, pyrrolidone carboxylic acid, cysteic acid and derivatives thereof, aldobionic acids, azelaic acid and derivates thereof, ascorbic acid and derivates thereof, nicotinic acid and esters thereof, nicotinamide, nordihydroguaiaretic acid, urea, oligofucoses, cinnamic acid, jasmonic acid derivatives, hydroxystilbenes,  Saccarum officinarum  extract, enzymes involved in the desquamation and degradation of corneodesmosomes, chelating agents, aminosulfonic chelating compounds, sodium methylglycine diacetic acid, derivatives of 2-oxothiazolidine-4-carboxylic acid, O-octanoyl-6-D-maltose, N-acetylglucosamine, chestnut extract, opuntia extract or combination of extracts of  Saphora japonica , papaya, pineapple, squash or sweet potato and mixtures thereof. 
     
     
         43 . A method according to  claim 39 , where the agents regulating keratinocyte differentiation or agents stimulating keratinocyte differentiation are selected from the group consisting of calcium, retinoids, vitamin D3 analogs, lupin extract, beta-sitosterol sulfate, corn seed extract,  Helix Aspersa  Müller glycoconjugates and mixtures thereof. 
     
     
         44 . A method according to  claim 39 , where the agents stimulating healing, coadjuvant healing agents or reepithelialization agents are selected from the group consisting of allantoin, cadherins, integrins, selectins, hyaluronic acid receptors, immunoglobulins, fibroblast growth factor, connective tissue growth factor, platelet derived growth factor, vascular endothelial growth factor, epidermal growth factor, insulin-like growth factor, keratinocyte growth factor, colony stimulating factors, transforming growth factors-beta, tumor necrosis factor-alpha, interferons, interleukins, matrix metalloproteases, protein tyrosine phosphatase receptors, Tripeptide-10 Citrulline, extract of  Aristoloquia clematis, Centella asiatica, Rosa moschata, Echinacea angustifolia, Symphytum officinal, Equisetum arvense, Hypericum perforatum, Mimosa tenuiflora, Persea gratisima, Prunus africanum, Tormentilla erecta, Aloe vera, Calendula Officinalis, Hypericum Perforatum, Chamomilla Recutita, Rosmarinus Officinalis , hydrolyzed casein, hydrolyzed yeast protein, corn kernel extract, and mixtures thereof. 
     
     
         45 . Cosmetic or dermopharmaceutical composition comprising  Pseudoalteromonas  ferment extract, glycerin, glucose, urea, shea butter and musk rose seed oil. 
     
     
         46 . Cosmetic or dermopharmaceutical composition comprising  Pseudoalteromonas  ferment extract, glycerin, proline, alanine and serine.