US2011196013A1PendingUtilityA1

Animal feed composition

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Assignee: GILLESSEN HUBERT JEAN MARIE FRANCOISPriority: Oct 3, 2003Filed: Apr 19, 2011Published: Aug 11, 2011
Est. expiryOct 3, 2023(expired)· nominal 20-yr term from priority
Inventors:Hubert Jean-Marie Francois GillessenChristian Rebiere
A61P 37/02A61P 37/04A61P 37/00A61P 5/00A61P 43/00A61P 1/14A23K 50/60C07D 209/18A23K 20/132A61K 31/7056Y10S426/805A61K 31/404A23K 50/80A23K 50/75A23K 20/184Y10S426/807A23K 50/30A61K 31/4045A61K 31/405A23K 20/168
41
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Claims

Abstract

The present invention relates to an animal feed composition that comprises free indole acetic acid (free IAA) or a derivative thereof. The invention also relates to a method for enhancing animal growth by feeding the animal with a composition according to the invention. The invention also relates to the use of free IAA or a derivative thereof in a method of therapy of animals in need of a growth-promoting treatment, such as immunocompromised animals, animals with a growth deficit or slow growing animals. The invention also relates to the use of free IAA or a derivative thereof for the preparation of a therapeutical composition for increasing the growth rate and/or the feed conversion rate and/or the immunity of animals in need of such a treatment, in particular immunocompromised or slow growing animals. A composition according to the invention may preferably be in the form of a food or feed supplement.

Claims

exact text as granted — not AI-modified
1 . An animal feed composition comprising more than 240 microgram of free IAA or a derivative thereof per kilogram. 
     
     
         2 . A feed composition according to  claim 1  comprising up to 40 g of free IAA or a derivative thereof per kilogram. 
     
     
         3 . A feed composition according to  claim 1  or  2  comprising between 100 and 1000 mg of free IAA or a derivative thereof per kilogram 
     
     
         4 . A feed composition according to  claims 1  to  3  additionally comprising an enzyme capable of converting the derivative into free IAA. 
     
     
         5 . A feed composition according to  claims 1  to  4  wherein the derivative is selected from the group consisting of 4-hydroxy-IAA, 4-methoxy-IAA, 5-hydroxy-IAA, 5-methoxy-IAA, 6-hydroxy-IAA, 6-methoxy-IAA, 7-hydroxy-IAA and 7-methoxy-IAA. 
     
     
         6 . A feed composition according to  claim 5  wherein the aromatic ring is substituted on one or more of the 4, 5, 6 and 7 position with methyl, amino, nitro, fluoride, chloride, bromide or iodide. 
     
     
         7 . A feed composition according to  claims 1  to  4  wherein the derivative can be converted into free IAA in more than 3 steps, preferably in 3, more preferably in 2 and most preferably in 1 step. 
     
     
         8 . A feed composition according to  claims 1  to  7  in the form of pellets, meal, grains, extruded or expanded grains, tablets, powder or bolus forms. 
     
     
         9 . A feed composition according to  claims 1  to  8  with a composition that is approved by a governmental institution. 
     
     
         10 . A method for increasing the growth rate and/or improving the feed efficiency and/or the feed conversion rate and/or the immunity of a non-human animal, the method comprising administering to said animal an effective amount of a composition according to  claims 1 - 9 . 
     
     
         11 . Use of free IAA or a derivative thereof for the preparation of a therapeutical composition for stimulating growth and/or stimulating the immune system in animals in need of such a treatment. 
     
     
         12 . Use according to  claim 11  wherein the free IAA or a derivative thereof is capable of increasing the serum level of insulin-like growth factor 1 (IGF-1). 
     
     
         13 . Use according to  claim 11  or  12  wherein the animal has a lowered level of IGF-1. 
     
     
         14 . Use according to  claims 11 - 13  wherein the animals have a growth deficit and/or a weakened immune system. 
     
     
         15 . Method for the preparation of an animal feed composition, said method comprising admixing a composition according to  claims 1 - 9  with one or more feed substance(s) or ingredient(s) in order to obtain an animal feed composition according to  claims 1 - 9 . 
     
     
         16 . Method for the preparation of an animal feed composition, said method comprising the step of supplementing an animal feed with free IAA or a derivative thereof in order to obtain an animal feed composition according to  claims 1 - 9 . 
     
     
         17 . Method for raising non-human animals comprising
 a) Mixing an effective dose of free IAA or a derivative thereof with a feed material suitable for a particular animal species   b) Feeding said species with the feed material

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