US2011207762A1PendingUtilityA1

Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone

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Assignee: PURDUE PHARMA LPPriority: Mar 30, 2004Filed: Sep 29, 2010Published: Aug 25, 2011
Est. expiryMar 30, 2024(expired)· nominal 20-yr term from priority
Inventors:Robert ChapmanLonn S. RiderQi-Zhong HongDonald J. KyleRobert Kupper
A61P 25/04A61P 29/00A61K 31/485A61K 9/4833A61K 9/48C07D 489/08C07D 489/04C07D 489/02A61K 9/2095A61K 9/20A61K 9/0053A61K 47/30A61K 9/14
63
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Claims

Abstract

In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

Claims

exact text as granted — not AI-modified
1 - 70 . (canceled) 
     
     
         71 : An oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone. 
     
     
         72 : The oxycodone hydrochloride composition of  claim 71 , having less than 15 ppm of 14-hydroxycodeinone. 
     
     
         73 : The oxycodone hydrochloride composition of  claim 71 , having less than 10 ppm of 14-hydroxycodeinone. 
     
     
         74 : The oxycodone hydrochloride composition of  claim 71 , having less than 5 ppm of 14-hydroxycodeinone. 
     
     
         75 : The oxycodone hydrochloride composition of  claim 71 , wherein the composition has a lower limit of 14-hydroxycodeinone of 0.25 ppm. 
     
     
         76 : The oxycodone hydrochloride composition of  claim 71 , wherein the composition a lower limit of 14-hydroxycodeinone of 0.5 ppm. 
     
     
         77 : The oxycodone hydrochloride composition of  claim 71 , wherein the composition has a lower limit of 14-hydroxycodeinone of 1 ppm. 
     
     
         78 : The oxycodone hydrochloride composition of  claim 71 , wherein the composition has a lower limit of 14-hydroxycodeinone of 2 ppm. 
     
     
         79 : The oxycodone hydrochloride composition of  claim 71 , wherein the composition has a lower limit of 14-hydroxycodeinone of 5 ppm.

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