Nasal devices

Abstract

Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described.

1 . A nasal device adapted to be secured in communication with a subject's nasal cavity, the device comprising:
 an airflow resistor configured to inhibit airflow during expiration more than airflow during inspiration; and   a flexible, adhesive holdfast and   wherein the airflow resistor is configured to have a resistance to expiration between about 5 cm H 2 O/(L/sec) and about 250 cm H 2 O/(L/sec) when resistance is measured at a flow rate of 100 ml/sec.   
     
     
         2 . The device of  claim 1 , wherein the flexible, adhesive holdfast extends outward from the airflow resistor. 
     
     
         3 . The device of  claim 1 , wherein the flexible, adhesive holdfast is configured to seal the nasal device around the subject's nostril. 
     
     
         4 . The device of  claim 1 , further comprising an internally-projecting region at least partially surrounding the airflow resistor configured to project into the subject's nostril. 
     
     
         5 . The device of  claim 1 , wherein the flexible, adhesive holdfast is adapted to be secured in communication with both of a subject's nostrils. 
     
     
         6 . The device of  claim 1 , further comprising a leak pathway through the nasal device configured to be open during both expiration and inspiration. 
     
     
         7 . The device of  claim 1 , wherein the airflow resistor comprises a flap valve. 
     
     
         8 . A nasal device adapted to be secured in communication with a subject's nasal cavity, the device comprising:
 an airflow resistor, wherein the airflow resistor is configured to inhibit airflow during expiration more than airflow during inspiration; and   a flexible, adhesive holdfast configured to seal the nasal device around the subject's nostril.   
     
     
         9 . The device of  claim 8 , wherein the flexible, adhesive holdfast extends outward from the airflow resistor. 
     
     
         10 . The device of  claim 8 , further comprising an internally-projecting region at least partially surrounding the airflow resistor configured to project into the subject's nostril. 
     
     
         11 . The device of  claim 8 , wherein the flexible, adhesive holdfast is adapted to be secured in communication with both of a subject's nostrils. 
     
     
         12 . The device of  claim 8 , further comprising a leak pathway through the nasal device configured to be open during both expiration and inspiration. 
     
     
         13 . The device of  claim 8 , wherein the airflow resistor comprises a flap valve. 
     
     
         14 . A nasal device adapted to be secured in communication with a subject's nasal cavity, the device comprising:
 an airflow resistor configured to inhibit airflow during expiration more than airflow during inspiration; and   a flexible, adhesive holdfast and   further comprising a protective cover configured to be removed from the adhesive holdfast to expose at least a portion of the biocompatible adhesive.   
     
     
         15 . The device of  claim 14 , wherein the flexible, adhesive holdfast extends outward from the airflow resistor. 
     
     
         16 . The device of  claim 14 , wherein the flexible, adhesive holdfast is configured to seal the nasal device around the subject's nostril. 
     
     
         17 . The device of  claim 14 , further comprising an internally-projecting region at least partially surrounding the airflow resistor configured to project into the subject's nostril. 
     
     
         18 . The device of  claim 14 , wherein the flexible, adhesive holdfast is adapted to be secured in communication with both of a subject's nostrils. 
     
     
         19 . The device of  claim 14 , further comprising a leak pathway through the nasal device configured to be open during both expiration and inspiration. 
     
     
         20 . The device of  claim 14 , wherein the airflow resistor comprises a flap valve.