Isolated lactobacillus plantarum strain inducia dsm 21379 as probiotic that enhances natural immunity and food products and medicinal preparations comprising it

Abstract

The present invention relates to a microorganism Lactobacillus plantarum strain Inducia DSM 21379 as probiotic, its functional properties, food product (e.g. cheese) and composition comprising said microorganism and use of said microorganism for production of medicine for enhancing cellular immunity. L. plantarum Inducia produces polyamines from ornithine and glutamate, nitric mono-oxide (NO) from arginine, possesses antioxidative activity and with produced polyamines, nitric mono-oxide and antioxidative compounds improves the intestinal barrier function, increases number of immunocytes in blood and induces cytokine production for enhancement of organisms' natural defense.

1 . An isolated probiotic microorganism strain  Lactobacillus plantarum  Inducia DSM 21379 that produces polyamines from ornithine and glutamate and nitric mono-oxide (NO) from arginine. 
     
     
         2 . The probiotic microorganism strain of  claim 1  in freeze-dried form. 
     
     
         3 . The isolated probiotic microorganism of  claim 1 , wherein said microorganism possesses antioxidative activity. 
     
     
         4 . The isolated probiotic microorganism of  claim 1 , wherein said microorganism is capable of inducing adaptively proinflammatory cytokines. 
     
     
         5 . The isolated probiotic microorganism of  claim 1 , wherein said microorganism is capable of enhancing the natural defense potential of human organism. 
     
     
         6 . The isolated probiotic microorganism of  claim 1 , wherein said microorganism is capable of improving the intestinal barrier function and increasing cellular immunity of the intestinal mucosa and blood. 
     
     
         7 . A composition for enhancing the natural defense potential of a human organism and cellular immunity comprising the probiotic microorganism of  claim 1 . 
     
     
         8 . The composition of  claim 7 , which is selected from the group consisting a pharmaceutical composition and a food composition. 
     
     
         9 . A food product comprising the probiotic microorganism of  claim 1 . 
     
     
         10 . The food product of  claim 9 , wherein the food product is a dairy product. 
     
     
         11 . The food product of  claim 10 , wherein the food product is a fermented milk product. 
     
     
         12 . The food product of  claim 11 , wherein the food product is cheese.