US2011277499A1PendingUtilityA1

Method for producing sterile cryogenic liquid

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Assignee: LEE RON CPriority: May 12, 2010Filed: May 12, 2010Published: Nov 17, 2011
Est. expiryMay 12, 2030(~3.8 yrs left)· nominal 20-yr term from priority
Inventors:Ron C. Lee
A61L 2/04A61L 2/022
40
PatentIndex Score
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Claims

Abstract

A method for producing a sterile cryogenic fluid from a cryogenic gas by sterilizing the cryogenic gas and using a heat exchanger to liquefy the sterile cryogenic stream. The discharge rate of the sterile cryogenic fluid is controlled by sizing the discharge orifice and setting a predetermined pressure of the sterile cryogenic fluid.

Claims

exact text as granted — not AI-modified
1 . An improved method for producing a sterile cryogenic fluid by sterilizing a cryogenic gas to produce a sterile cryogenic stream and feeding the sterilized cryogenic stream to a heat exchanger to liquefy the sterile cryogenic stream, the improvement comprising controlling the discharge rate of sterile cryogenic fluid by sizing the discharge orifice and setting a predetermined pressure of the sterile cryogenic fluid. 
     
     
         2 . The method as claimed in  claim 1  wherein said cryogenic fluid is selected from the group of liquids having a normal boiling point below −50° C. 
     
     
         3 . The method as claimed in  claim 2  wherein said cryogenic fluid is selected from the group consisting of nitrogen, oxygen, liquid air and argon. 
     
     
         4 . The method as claimed in  claim 1  wherein said sterilizing is warm sterilization by filtration. 
     
     
         5 . The method as claimed in  claim 1  further comprising steam sterilization of said heat exchanger and discharge orifice. 
     
     
         6 . The method as claimed in  claim 1  wherein said discharge orifice provides a flow restriction of sterile cryogenic fluid. 
     
     
         7 . The method as claimed in  claim 1  wherein said discharge orifice is selected from the group consisting of orifices, nozzles, and piping. 
     
     
         8 . The method as claimed in  claim 1  wherein the pressure of said cryogenic gas is sufficient to allow liquefaction in said heat exchanger. 
     
     
         9 . The method as claimed in  claim 1  wherein said heat exchanger has sufficient surface area to condense said cryogenic gas. 
     
     
         10 . The method as claimed in  claim 1  wherein said predetermined pressure is greater than atmospheric pressure. 
     
     
         11 . An improved method for the production of a sterile cryogenic fluid comprising controlling the flow rate of the sterile cryogenic fluid by controlling the pressure of the sterilized cryogenic fluid and an orifice that dispenses the sterile cryogenic fluid. 
     
     
         12 . The method as claimed in  claim 11  wherein said cryogenic fluid is selected from the group of liquids having a normal boiling point below −50° C. 
     
     
         13 . The method as claimed in  claim 12  wherein said cryogenic fluid is selected from the group consisting of nitrogen, oxygen, liquid air and argon. 
     
     
         14 . The method as claimed in  claim 11  wherein said sterilizing is warm sterilization by filtration. 
     
     
         15 . The method as claimed in  claim 11  further comprising steam sterilization of said heat exchanger and discharge orifice. 
     
     
         16 . The method as claimed in  claim 11  wherein said discharge orifice provides a constant flow restriction of sterile cryogenic fluid. 
     
     
         17 . The method as claimed in  claim 11  wherein said discharge orifice is selected from the group consisting of orifices, nozzles, and piping. 
     
     
         18 . The method as claimed in  claim 11  wherein the pressure of said cryogenic gas is sufficient to allow liquefaction in said heat exchanger. 
     
     
         19 . The method as claimed in  claim 11  wherein said heat exchanger has sufficient surface area to condense said cryogenic gas. 
     
     
         20 . The method as claimed in  claim 11  wherein said predetermined pressure is greater than atmospheric pressure. 
     
     
         21 . A method for controlling the flow of a sterile cryogenic fluid from a discharge orifice comprising sizing the discharge orifice by controlling the pressure and the flow of the sterile cryogenic fluid. 
     
     
         22 . The method as claimed in  claim 21  wherein said cryogenic fluid is selected from the group of liquids having a normal boiling point below −50° C. 
     
     
         23 . The method as claimed in  claim 22  wherein said cryogenic fluid is selected from the group consisting of nitrogen, oxygen, liquid air and argon. 
     
     
         24 . The method as claimed in  claim 21  further comprising steam sterilization of said heat exchanger and discharge orifice. 
     
     
         25 . The method as claimed in  claim 21  wherein said discharge orifice provides a flow restriction of sterile cryogenic fluid. 
     
     
         26 . The method as claimed in  claim 21  wherein said discharge orifice is selected from the group consisting of orifices, nozzles, and piping. 
     
     
         27 . A process for producing sterile cryogenic fluids at a predetermined flow rate at a predetermined pressure comprising sizing the discharge orifice of the production process to deliver the sterile cryogenic fluids. 
     
     
         28 . The method as claimed in  claim 27  wherein said cryogenic fluid is selected from the group of liquids having a normal boiling point below −50° C. 
     
     
         29 . The method as claimed in  claim 28  wherein said cryogenic fluid is selected from the group consisting of nitrogen, oxygen, liquid air and argon. 
     
     
         30 . The method as claimed in  claim 27  wherein said sterilizing is warm sterilization by filtration. 
     
     
         31 . The method as claimed in  claim 27  further comprising steam sterilization of said heat exchanger and discharge orifice. 
     
     
         32 . The method as claimed in  claim 27  wherein said discharge orifice provides a constant flow restriction of sterile cryogenic fluid. 
     
     
         33 . The method as claimed in  claim 27  wherein said discharge orifice is selected from the group consisting of orifices, nozzles, and piping. 
     
     
         34 . The method as claimed in  claim 27  wherein said predetermined pressure is greater than atmospheric pressure.

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