US2011281022A1PendingUtilityA1

Methods For Controlling The Release Rate And Improving The Mechanical Properties Of A Stent Coating

Assignee: HOSSAINY SYED FAIYAZ AHMEDPriority: Sep 8, 2006Filed: Jul 26, 2011Published: Nov 17, 2011
Est. expirySep 8, 2026(~0.1 yrs left)· nominal 20-yr term from priority
A61L 31/16A61L 2300/602A61L 31/08C08L 27/20A61L 31/14A61L 2300/416
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Claims

Abstract

Methods for controlling the release rate and improving the mechanical properties of a stent coating are disclosed.

Claims

exact text as granted — not AI-modified
1 . A method comprising:
 exposing a stent coated with paclitaxel and SIBS to either (1) electron beam radiation or (2) gamma radiation in the presence of oxygen, wherein the radiation acts to decrease the degree of cross-linking of the SIBS, thereby providing a means for controlling the paclitaxel release rate and improving the mechanical properties of the coating.   
     
     
         2 . The method of  claim 1 , wherein the exposure is to electron beam radiation. 
     
     
         3 . The method of  claim 1 , wherein the exposure is to gamma radiation.

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