Methods and Compositions for the Production of High Concentration Alloxazine Solutions

Abstract

Methods are provided for preparation of compositions having an enhanced level of soluble alloxazine, as compared to compositions prepared using conventional techniques. Compositions and a riboflavin form having higher solubility in solution is also provided.

1 . A composition for treating a blood product comprising:
 between about 150 μM and about 580 μM soluble alloxazine; and   a monovalent salt.   
     
     
         2 . The composition of  claim 1  wherein the soluble alloxazine is a concentration of about 580 μM. 
     
     
         3 . The composition of  claim 1  wherein the alloxazine is riboflavin. 
     
     
         4 . The composition of  claim 1  further comprising sodium bicarbonate. 
     
     
         5 . The composition of  claim 1  wherein the composition has a pH of from about 4 to about 5. 
     
     
         6 . The composition of  claim 1  wherein the monovalent salt provides a salinity of at least 0.9%.