US2011319987A1PendingUtilityA1

Medical implant

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Assignee: PALASIS MARIAPriority: May 20, 2009Filed: Jul 14, 2011Published: Dec 29, 2011
Est. expiryMay 20, 2029(~2.9 yrs left)· nominal 20-yr term from priority
Inventors:Maria PalasisChang Cheng YouDaniel ConcaghLee CoreKicherl HoUpma SharmaGreg Zugates
A61F 2210/0004A61F 2/90A61F 2250/0018A61L 2420/02A61F 2210/0014A61F 2230/0054A61F 2250/0036A61F 2/07A61L 2300/606A61L 31/16A61L 31/10A61F 2250/0048A61L 31/06
45
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Claims

Abstract

Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties.

Claims

exact text as granted — not AI-modified
1 . A polymer coating composition prepared by a process comprising the steps of:
 dissolving poly (lactic acid-co-caprolactone) in a solvent to form a solution;   adding a diisocyanate crosslinker to the solution; and   curing said solution;   
       wherein said solution does not comprise a catalyst. 
     
     
         2 . The polymer coating composition of  claim 1 , wherein said diisocyanate crosslinker is hexamethylene diisocyanate. 
     
     
         3 . The polymer coating composition of  claim 1 , wherein said poly (lactic acid-co-caprolactone) comprises about 50 weight percent of lactic acid and about 50 weight percent of caprolactone. 
     
     
         4 . The polymer coating composition of  claim 1 , wherein said solution comprises about 0.125 mL of said diisocyanate crosslinker to every 1.0 grams of poly (lactic acid-co-caprolactone). 
     
     
         5 . The polymer coating composition of  claim 4 , wherein said diisocyanate crosslinker is hexamethylene diisocyanate. 
     
     
         6 . The polymer coating composition of  claim 4 , wherein said solution comprises about 19.875 mL of a solvent to every 1.0 grams of poly (lactic acid-co-caprolactone). 
     
     
         7 . The polymer coating composition of  claim 6 , wherein said solvent comprises methylene chloride. 
     
     
         8 . A medical implant comprising a coating, said coating prepared by a process comprising the steps of:
 dissolving poly (lactic acid-co-caprolactone) in a solvent to form a solution;   adding a diisocyanate crosslinker to the solution; and   curing said solution;   
       wherein said solution does not comprise a catalyst. 
     
     
         9 . The medical implant of  claim 8 , wherein said diisocyanate crosslinker is hexamethylene diisocyanate. 
     
     
         10 . The medical implant of  claim 8 , wherein said poly (lactic acid-co-caprolactone) comprises about 50 weight percent of lactic acid and about 50 weight percent of caprolactone. 
     
     
         11 . The medical implant of  claim 8 , wherein said solution comprises about 0.125 mL of said diisocyanate crosslinker to every 1.0 grams of poly (lactic acid-co-caprolactone). 
     
     
         12 . The medical implant of  claim 11 , wherein said diisocyanate crosslinker is hexamethylene diisocyanate. 
     
     
         13 . The medical implant of  claim 11 , wherein said solution comprises about 19.875 mL of a solvent to every 1.0 grams of poly (lactic acid-co-caprolactone). 
     
     
         14 . The medical implant of  claim 13 , wherein said solvent comprises methylene chloride. 
     
     
         15 . The medical implant of  claim 8 , wherein said implant comprises polymeric strands coated with said coating. 
     
     
         16 . The medical implant of  claim 15 , wherein said strands comprise poly(lactic acid co-glycolic acid). 
     
     
         17 . The medical implant of  claim 16 , wherein said poly(lactic acid co-glycolic acid) comprises about 85 weight percent of lactic acid and about 15 weight percent of glycolic acid. 
     
     
         18 . A medical implant comprising a coating, said implant prepared by a process comprising the steps of:
 providing an implant comprising braided polymeric strands;   dissolving poly (lactic acid-co-caprolactone) in a solvent to form a solution;   adding a diisocyanate crosslinker to the solution;   coating said solution onto said polymeric strands; and   curing said solution;   
       wherein said solution does not comprise a catalyst. 
     
     
         19 . The medical implant of  claim 18 , wherein said polymeric strands are biodegradable. 
     
     
         20 . The medical implant of  claim 19 , wherein said strands comprise poly(lactic acid co-glycolic acid). 
     
     
         21 . The medical implant of  claim 20 , wherein said poly(lactic acid co-glycolic acid) comprises about 85 weight percent of lactic acid and about 15 weight percent of glycolic acid. 
     
     
         22 . The medical implant of  claim 18 , wherein said diisocyanate crosslinker is hexamethylene diisocyanate. 
     
     
         23 . The medical implant of  claim 18 , wherein said poly (lactic acid-co-caprolactone) comprises about 50 weight percent of lactic acid and about 50 weight percent of caprolactone. 
     
     
         24 . The medical implant of  claim 18 , wherein said solution comprises about 0.125 mL of said diisocyanate crosslinker to every 1.0 grams of poly (lactic acid-co-caprolactone). 
     
     
         25 . The medical implant of  claim 24 , wherein said diisocyanate crosslinker is hexamethylene diisocyanate.

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