Cosmetic composition containing a particular water, and use thereof as a depigmenting or anti-ageing agent

Abstract

The invention relates to the use, in a cosmetic or dermatological composition, of a particular water having a pH of between 7.8 and 10 and a total dissolved solids (TDS) concentration of between 10 and 250 mg/l. The invention also relates to a cosmetic or dermatological composition containing this water. The invention relates in particular to a treatment method intended for preventing or delaying the appearance of the effects of intrinsic and/or extrinsic ageing of the skin, or for slowing down the effects thereof; for preventing or reducing pigmentary spots on the skin, or the coloration of hyperpigmented areas of skin; for reducing the pigmentation of the periphery of depigmented areas; for improving the uniformity of the skin coloration; or for lightening the complexion of the skin.

1 . Cosmetic or dermatological composition comprising at least one water having:
 a pH of between 7.6 and 10, preferably between 7.8 and 8.8, and   a total dissolved solids (TDS) concentration of between 10 and 250 mg/l, preferably between 20 and 100 mg/l.   
     
     
         2 . Composition according to  claim 1 , wherein the concentration by weight of water relative to the total weight of the composition is from 10% to 99%. 
     
     
         3 . Composition according to  claim 1 , wherein the composition is a topical composition. 
     
     
         4 . Composition according to  claim 1  further comprising at least one other active agent or at least one cosmetically or dermatologically acceptable excipient. 
     
     
         5 . Cosmetic or dermatological composition according to  claim 1 , wherein the water comprises the following concentrations:
 calcium (Ca 2+ ) between 3 and 14 mg/l, and preferably between 4 and 10 mg/l;   chloride (CO between 2 and 16 mg/l, and preferably between 8 and 14 mg/l;   magnesium (Mg 2+ ) between 0.8 and 5 mg/l, and preferably between 0.8 and 3 mg/l;   potassium (r) between 0.01 and 2 mg/l, and preferably between 0.1 and 1 mg/l;   sodium (Na + ) between 2 and 14 mg/l, and preferably between 8 and 13 mg/l;   bicarbonates (HCO 3   − ) between 0 and 50 mg/l, and preferably between 10 and 40 mg/l;   sulphates (SO 4   2 ) between 1 and 5 mg/l, and preferably between 2 and 5 mg/l.   
     
     
         6 . Cosmetic or dermatological composition according to  claim 1 , wherein the water has a pH of between 8.2 and 8.8. 
     
     
         7 . Cosmetic or dermatological composition according to  claim 1 , wherein the water has a total dissolved solids (TDS) concentration of between 40 and 80 mg/l. 
     
     
         8 . Cosmetic or dermatological composition according to  claim 1 , wherein the water has the following composition:
 calcium (Ca 2+ ) approximately 6.4 mg/l;   chlorine (Cl − ) approximately 13 mg/l;   magnesium (Mg 2+ ) approximately 2.4 mg/l;   potassium (K + ) approximately 0.6 mg/l;   sodium (Na + ) approximately 12 mg/l;   bicarbonates (HCO 3   − ) approximately 33 mg/l;   sulphates (SO 4   2− ) approximately 3.4 mg/l;   wherein the water has a total dissolved solids (TDS) concentration of approximately 62 mg/l; and   wherein the water has a pH of approximately 8.4.   
     
     
         9 . Cosmetic or dermatological composition according to  claim 1 , wherein the water has the following composition:
 calcium (Ca 2+ ) approximately 4.6 mg/l;   chlorine (Cl − ) approximately 11.0 mg/l;   magnesium (Mg 2+ ) approximately 0.9 mg/l;   potassium (K + ) approximately 0.5 mg/l;   sodium (Na + ) approximately 12 mg/l;   sulphates (SO 4   2− ) approximately 2.3 mg/l;   wherein the water has a total dissolved solids (TDS) concentration of approximately 48 mg/l; and   wherein the water has a pH of approximately 8.7.   
     
     
         10 . Cosmetic or dermatological composition according to  claim 1 , wherein the water has the following composition:
 calcium (Ca 2+ ) approximately 12.5 mg/l;   chlorine (Cl − ) approximately 3.8 mg/l;   magnesium (Mg 2+ ) approximately 1.3 mg/l;   potassium (K + ) approximately 0.4 mg/l;   sodium (Na + ) approximately 3 mg/l;   sulphates (SO 4   2− ) approximately 6.9 mg/l;   wherein the water has a total dissolved solids (TDS) concentration of approximately 56 mg/l; and   wherein the water has a pH of approximately 8.3.   
     
     
         11 . Cosmetic or dermatological composition according to  claim 1 , wherein the concentration by weight of water relative to the total weight of the composition is at least 15%, preferably at least 40%, preferably at least 60%, and more preferably at least 80%. 
     
     
         12 . Cosmetic or dermatological composition according to  claim 1 , wherein the composition is:
 a composition for preventing or delaying the appearance of the signs of intrinsic and/or extrinsic ageing of the skin, or for slowing down the effects thereof, and/or   a composition for depigmenting, bleaching or lightening the skin and keratin fibres.   
     
     
         13 . Cosmetic or dermatological composition according to  claim 1 , wherein it is formulated in the form of a solution, serum, lotion, spray, milk, emulsion, preferably oil-in-water emulsion, or hydrogel. 
     
     
         14 . A method of treatment selected from the group consisting of
 depigmenting, bleaching or lightening the keratin materials,   inhibiting the expression of the gene encoding Tyrosinase Related Protein-1 (TRP-1) and/or of the gene encoding tyrosinase,   protecting and preventing extrinsic and/or intrinsic ageing of the skin, or slowing down the effects thereof,   preventing or reducing pigmentary spots on the skin (areas of hyperpigmentation) or the coloration of hyperpigmented areas of skin, in particular those consisting of various dyschromias of the skin, in particular contact dermatoses, drug-induced photodermatoses, melasma, keratoses, for example senile or actinic keratoses, senile lentigo (age spots) or solar lentigo, pigmentary spots resulting from scars or burns, or pigmentary spots induced by allergic or phototoxic reactions,   preventing or reducing the pigmentation of the periphery of depigmented areas, in particular induced by leucoderma such as vitiligo,   improving the uniformity of the skin coloration, or lightening the complexion of the skin,   said method comprising applying to keratin materials, such as skin or keratin fibres, of a subject in need thereof, an effective amount of a composition according to  claim 1  or an effective amount of a water having:
 a pH of between 7.6 and 10, preferably between 7.8 and 8.8, and 
 a total dissolved solids (TDS) concentration of between 10 and 250 mg/l, preferably between 20 and 100 mg/l. 
   
     
     
         15 . The method according to  claim 14 , wherein the water comprises the following concentrations:
 calcium (Ca 2+ ) between 3 and 14 mg/l, and preferably between 4 and 10 mg/l;   chloride (Cl − ) between 2 and 16 mg/l, and preferably between 8 and 14 mg/l;   magnesium (Mg 2+ ) between 0.8 and 5 mg/l, and preferably between 0.8 and 3 mg/l;   potassium (K + ) between 0.01 and 2 mg/l, and preferably between 0.1 and 1 mg/l;   sodium (Na + ) between 2 and 14 mg/l, and preferably between 8 and 13 mg/l;   bicarbonates (HCO 3   − ) between 0 and 50 mg/l, and preferably between 10 and 40 mg/l;   sulphates (SO 4   2− ) between 1 and 5 mg/l, and preferably between 2 and 5 mg/l.   
     
     
         16 . The method according to  claim 14 , wherein the water has a pH of between 8.2 and 8.8. 
     
     
         17 . The method according to  claim 14 , wherein the water has a total dissolved solids (TDS) concentration of between 40 and 80 mg/l. 
     
     
         18 . The method according to  claim 14 , wherein said method is a cosmetic care method. 
     
     
         19 . The method according to  claim 14 , wherein the composition is a dermatological composition.