6-11 Bicyclic Ketolide Derivatives

Abstract

The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

1 . A compound represented by formula: 
       
         
           
           
               
               
           
         
         and pharmaceutically acceptable salts, esters, prodrugs, racemic mixtures and stereoisomers thereof.