Tissue Plug

Abstract

Tissue plugs for occlusion of hollow anatomical structures and methods for their use are provided.

1 . A device for treatment of hollow anatomical structures comprising:
 a. a first portion;   b. a first axial member which is oriented through a hollow anatomical structure and is connected to the first portion; and   c. at least one occluding member which adjusts upon said first axial member to fill the hollow anatomical structure.   
     
     
         2 . The device of  claim 1  wherein the first portion is in the form of a fixed point or an anchoring member. 
     
     
         3 . The device of  claim 2  wherein the first portion is in the form of a substantially planar anchoring member. 
     
     
         4 . The device of  claim 1  wherein the occluding member adjusts within the hollow anatomical structure upon longitudinal translation along the axial member. 
     
     
         5 . The device of  claim 4  further comprising a second portion connected to said first axial member. 
     
     
         6 . The device of  claim 5  wherein the first portion is either fixedly or slidably connected to the first axial member and wherein the second portion is either fixedly or slidably connected to the first axial member provided that the first portion and the second portion are not both fixedly attached to the first axial member. 
     
     
         7 . The device of  claim 4  further comprising a second axial member. 
     
     
         8 . The device of  claim 7  further comprising a second portion that is connected to said second axial member. 
     
     
         9 . The device of  claim 8  wherein the first portion is fixedly or slidably connected to the first axial member and the second portion is fixedly or slidably connected to the second axial member 
     
     
         10 . The device of  claim 5  wherein the first portion and the second portion are in the form of a fixed point or an anchoring member. 
     
     
         11 . The device of  claim 10  wherein the first portion and the second portion are in the form of a substantially planar anchoring member. 
     
     
         12 . The device of  claim 1  wherein the at least one occluding member is bioabsorbable. 
     
     
         13 . The device of  claim 1  further comprising a collar attached to at least one end of the at least one occluding member. 
     
     
         14 . The device of  claim 13  wherein said collar reduces the freedom of movement of any components which may move or slide along the first axial member after deployment. 
     
     
         15 . The device of  claim 14  wherein said collar reduces the freedom of movement via chemical, mechanical or frictional means. 
     
     
         16 . The device of  claim 1  further comprising a first portion reinforcement element. 
     
     
         17 . The device of  claim 5  further comprising first portion and second portion reinforcement elements. 
     
     
         18 . The device of  claim 2  wherein the device is adapted for catheter delivery. 
     
     
         19 . The device of  claim 18  wherein said at least one occluding member is collapsible from an initial state with an initial length to a deployed state with a length shorter than said initial length and wherein said deployed occluding member conforms to the geometry of a tract formed by the hollow anatomical structure. 
     
     
         20 . The device of  claim 19  wherein said first portion is an anchoring member which is expandable from an initial state with an initial diameter to a deployed state with a diameter greater than said initial diameter. 
     
     
         21 . The device of  claim 20  wherein the device is adapted to be undeployable and redeployable. 
     
     
         22 . The device of  claim 5  wherein the device is adapted for catheter delivery. 
     
     
         23 . The device of  claim 22  wherein said at least one occluding member is collapsible from an initial state with an initial length to a deployed state with a length shorter than said initial length and wherein said deployed occluding member conforms to the geometry of a tract formed by the hollow anatomical structure. 
     
     
         24 . The device of  claim 23  wherein said first portion and said second portion are anchoring members which are expandable from an initial state with an initial diameter to a deployed state with a diameter greater than said initial diameter. 
     
     
         25 . The device of  claim 24  wherein the device is adapted to be undeployable and redeployable. 
     
     
         26 . A method of occluding a hollow anatomical structure by the steps of:
 a. providing an implantable device comprising at least a first portion and at least one occluding member;   b. positioning the first portion adjacent to one end of the hollow anatomical structure; and   c. bunching the occluding member and thereby filling a tract formed by the hollow anatomical structure while maintaining the position of the first portion.   
     
     
         27 . The method of  claim 21  wherein the implantable device further comprises a second portion. 
     
     
         28 . The method of  claim 22  wherein the second portion is positioned at the opposite end of the tract of the hollow anatomical structure upon bunching of the at least one occluding member. 
     
     
         29 . A device for treatment of hollow anatomical structure comprising:
 a. a first portion with an aperture extending there through;   b. a first axial member which is oriented through a hollow anatomical structure and is connected to the first portion; and   c. at least one occluding member which adjusts upon said axial portion to fill the hollow anatomical structure.   
     
     
         30 . The device of  claim 29  wherein the aperture is adapted for use with a guidewire. 
     
     
         31 . The device of  claim 10  wherein the first portion and the second portion are anchoring members and wherein at least one anchoring member is non-bioabsorbable. 
     
     
         32 . The device of  claim 31  wherein a non-bioabsorbable anchoring member is adapted to be positioned within a gastrointestinal tract of a patient.