Composition containing a bean extract for improving blood circulation and increasing vascular health

Abstract

The present invention relates to a composition containing a bean extract extracted by low-concentration, low-grade alcohol or fractions thereof. The composition exhibits excellent effects in improving blood circulation, improving obesity, and preventing diabetes, hyperlipidemia and the like, and exhibits the effects of alleviating or treating the symptoms of diabetes, hyperlipidemia, and the like. The present invention also relates to a method for improving blood circulation and vascular health.

1 . A method for improving blood circulation of a subject, comprising administering to the subject an effective amount of a bean extract extracted with a C 1 -C 5  alcohol with a concentration of 1-70% (v/v) or a fraction thereof, wherein the bean extract or the fraction thereof improves blood circulation in the subject. 
     
     
         2 . The method according to  claim 1 , wherein the C 1 -C 5  alcohol is at least one selected from a group consisting of methanol, ethanol, isopropyl alcohol, n-propyl alcohol, n-butanol and isobutanol. 
     
     
         3 . The method according to  claim 2 , wherein the C 1 -C 5  alcohol is ethanol. 
     
     
         4 . The method according to  claim 1 , wherein the bean extract or the fraction thereof comprises adenosine. 
     
     
         5 . The method according to  claim 4 , wherein the adenosine is included in an amount of 0.01-1.0 wt % based on the weight of the bean extract or the fraction thereof. 
     
     
         6 . The method according to  claim 1 , wherein the bean is at least one selected from a group consisting of Seoritae, Seomoktae, Black soybean, blue bean, yellow bean, field bean, kidney bean, pinto bean, small red bean, small black bean, sprouting bean and soybean. 
     
     
         7 . The method according to  claim 1 , wherein the bean is Seoritae or field bean. 
     
     
         8 . The method according to  claim 1 , wherein the fraction is an ethyl acetate or butanol fraction of a C 1 -C 5  alcohol extract. 
     
     
         9 . The method according to  claim 1 , wherein the bean extract or the fraction thereof improves blood circulation through suppression of blood clotting, suppression of vasoconstriction or suppression of cholesterol generation. 
     
     
         10 . The method according to  claim 1 , wherein the bean extract or the fraction thereof improves vascular health. 
     
     
         11 . (canceled) 
     
     
         12 . The method according to  claim 1 , wherein the method is for preventing, alleviating or treating obesity, diabetes, stroke, cerebral hemorrhage, arteriosclerosis, angina, myocardial infarction, hypertension, anemia, migraine or hyperlipidemia. 
     
     
         13 . A health food composition comprising a bean extract extracted with a C 1 -C 5  alcohol with a concentration of 1-70% (v/v) or a fraction thereof. 
     
     
         14 . (canceled) 
     
     
         15 . The health food composition according to  claim 13 , wherein the bean is at least one selected from a group consisting of Seoritae, Seomoktae, Black soybean, blue bean, yellow bean, field bean, kidney bean, pinto bean, small red bean, small black bean, sprouting bean and soybean. 
     
     
         16 . The health food composition according to  claim 15 , wherein the bean is Seoritae or field bean. 
     
     
         17 . The health food composition according to  claim 13 , wherein the fraction is an ethyl acetate or butanol fraction of a C 1 -C 5  alcohol extract. 
     
     
         18 . A pharmaceutical composition comprising a bean extract extracted with a C 1 -C 5  alcohol with a concentration of 1-70% (v/v) or a fraction thereof. 
     
     
         19 . The pharmaceutical composition according to  claim 18 , wherein the bean is at least one selected from a group consisting of Seoritae, Seomoktae, Black soybean, blue bean, yellow bean, field bean, kidney bean, pinto bean, small red bean, small black bean, sprouting bean and soybean. 
     
     
         20 . The pharmaceutical composition according to  claim 19 , wherein the bean is Seoritae or field bean. 
     
     
         21 . The pharmaceutical composition according to  claim 18 , wherein the fraction is an ethyl acetate or butanol fraction of a C 1 -C 5  alcohol extract.