Method of fixing rail molecule and nano transport device

Abstract

An object is to move a rail molecule by means of a biomolecular motor deposited on a base and inactivate the biomolecular motor through irradiation with light having a predetermined wavelength, to thereby readily and reliably fix the rail molecule at a predetermined position, while orienting the rail molecule in a predetermined direction without employment of any reagent. A method for fixing a rail molecule which has polarity and on which a biomolecular motor moves in a direction corresponding to the polarity includes depositing a biomolecular motor on a base; moving a rail molecule by means of the biomolecular motor; and inactivating the biomolecular motor by irradiating the biomolecular motor with light having a predetermined wavelength when the rail molecule reaches a predetermined position, to thereby fix the rail molecule so that it is oriented in a predetermined direction.

1 - 10 . (canceled) 
     
     
         11 . A rail molecule fixing method for fixing a rail molecule which has polarity and on which a biomolecular motor moves in a direction corresponding to the polarity, the method comprising:
 (a) depositing a biomolecular motor on a base;   (b) moving a rail molecule by means of the biomolecular motor; and   (c) inactivating the biomolecular motor by irradiating the biomolecular motor with light having a predetermined wavelength when the rail molecule reaches a predetermined position, to thereby fix the rail molecule so that it is oriented in a predetermined direction.   
     
     
         12 . A rail molecule fixing method according to  claim 11  further comprising:
 (a) attaching a channel-forming member onto the base, to thereby form an orientation channel on the base; 
 (b) causing the rail molecule to enter the orientation channel through one end of the orientation channel; and 
 (c) fixing the rail molecule at a predetermined position in the orientation channel. 
 
     
     
         13 . A rail molecule fixing method according to  claim 12 , wherein the channel-forming member is removed after fixation of the rail molecule. 
     
     
         14 . A rail molecule fixing method according to  claim 11 , wherein the rail molecule is a cytoskeletal filament. 
     
     
         15 . A rail molecule fixing method according to  claim 11 , wherein the predetermined wavelength is 420 to 500 nm. 
     
     
         16 . A rail molecule fixing method according to  claim 11 , wherein the biomolecular motor is irradiated with light for 60 seconds or more. 
     
     
         17 . A rail molecule fixing method according to  claim 11 , wherein a plurality of rail molecules are fixed so that they are aligned in parallel with one another and are oriented in the same direction. 
     
     
         18 . A rail molecule fixing method according to  claim 11 , wherein the rail molecule is fixed in the form of a curve or a bent line.