Therapeutic Compositions And Methods

Abstract

The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision.

1 . A method of treating macular degeneration comprising:
 1) providing:
 i) a subject diagnosed with macular degeneration and 
 ii) a composition comprising tetramethylpyrazine or salt thereof and 
   2) administering said compound to said subject.   
     
     
         2 . The method of  claim 1 , wherein said macular degeneration is age-related. 
     
     
         3 . The method of  claim 1 , wherein said subject is a human. 
     
     
         4 . The method of  claim 1 , wherein said administration is topically to the eye. 
     
     
         5 . The method of  claim 1 , wherein said salt is a hydrochloride salt. 
     
     
         6 . The method of  claim 1 , wherein said composition is a liquid solution. 
     
     
         7 . A method of treating macular degeneration comprising:
 1) providing
 i) a subject diagnosed with macular degeneration and 
 ii) a composition comprising a substituted or unsubstituted compound of the following formula: 
   
       
         
           
           
               
               
           
         
         
           or salt thereof functioning to decrease choroidal neovascularization and 
         
         2) administering said compound to said subject. 
       
     
     
         8 - 21 . (canceled)