Nucleic Acid and Amino Acid Sequences of Infectious Salmon Anaemia Virus and Their Use as Vaccines

Abstract

The present invention provides the use of nucleic acid sequences and/or amino acid sequences in the preparation of a vaccine for the protection of fish against infectious salmon anaemia virus. Specifically, such vaccines contain at least one nucleic acid sequence which is derived from ISAV or synthetically prepared analogues thereof, or substantially homologous sequences. These nucleic acid sequences are transcripted and translated into peptide sequences which are incorporated into a vaccination strategy to induce and immune response to the surface antigens of ISAV and therefore ISAV itself. Therefore both the use of a vaccine against ISAV, and the incorporation of peptide sequences is herein described.

1 - 13 . (canceled) 
     
     
         14 . A composition comprising a polypeptide having an amino acid sequence that is at least 70% homologous to SEQ ID NO: 10, wherein the polypeptide binds to an antibody obtained from an animal infected with ISAV and wherein the antibody binds to a protein having SEQ ID NO: 10. 
     
     
         15 . The composition of  claim 14 , wherein the polypeptide has an amino acid sequence that is at least 80% homologous to SEQ ID NO: 10. 
     
     
         16 . The composition of  claim 14 , wherein the polypeptide has an amino acid sequence that is at least 90% homologous to SEQ ID NO: 10.