US2012108519A1PendingUtilityA1

Neo-tryptophan

Assignee: RICHELSON ELLIOTTPriority: Apr 10, 1998Filed: Dec 13, 2011Published: May 3, 2012

Est. expiryApr 10, 2018(expired)· nominal 20-yr term from priority

Inventors:Elliott Richelson Bernadette Marie Cusack Yuan-Ping Pang Daniel J. Mccormick Abdul Fauq Beth Marie Tyler Mona Boules

C07D 209/08C07K 14/702C07K 7/18C07K 7/083C07K 14/70C07K 7/14A61K 38/00A61P 29/00A61P 25/04

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Abstract

Methods of inducing antinociception in a human are described. The method includes the step of administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human extracranially. The polypeptide containing L-neo-tryptophan could be, but is not limited to, NT64L, NT65L, NT66L, NT67L, NT69L, NT69L′, NT71, NT72, NT73, NT74, NT75, NT76, or NT77.

Claims

exact text as granted — not AI-modified

1 . A method of inducing antinociception in a human, said method comprising administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human extracranially. 
     
     
         2 . The method of  claim 1 , wherein the polypeptide is selected from the group consisting of NT64L, NT65L, NT66L, NT67L, NT69L, NT69L′, NT71, NT72, NT73, NT74, NT75, NT76, and NT77. 
     
     
         3 . A method of inducing antinociception in a human, said method comprising administering an effective dose of one or more of NT64L, NT65L, NT66L, NT67L, NT69L, NT69L′, NT71, NT72, NT73, NT74, NT75, NT76, and NT77.

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