Implant material and production method thereof

Abstract

The present invention provides an implant material comprising an organic-inorganic complex porous article and a production method thereof. The organic-inorganic complex porous article is a biodegradable and bioabsorbable bioactive porous article in which a bioactive bioceramics powder is uniformly dispersed in a biodegradable and bioabsorbable polymer, wherein it has continuous pores and the bioceramics powder is partly exposed to the pore inner surface or the pore inner surface and the porous article surface.

1 . An organic-inorganic complex implant article comprising (i) a biodegradable and bioabsorbable bioactive porous article in which a bioactive bioceramics powder is uniformly dispersed in a biodegradable and bioabsorbable polymer, wherein the biodegradable and bioabsorbable bioactive porous article has continuous pores having a pore size of approximately from 100 to 400 μm, wherein the bioceramics powder is partly exposed to the pore inner surface or the pore inner surface and the porous article surface, and wherein porosity of the aforementioned porous article is from 50 to 90%, and (ii) a compact biodegradable and bioabsorbable member united thereto. 
     
     
         2 . The organic-inorganic complex implant article described in  claim 1 , wherein the compact biodegradable and bioabsorbable member is a matrix having a cavity opening into the outside that comprises a biodegradable and bioabsorbable polymer containing a bioactive bioceramics powder, wherein the biodegradable and bioabsorbable bioactive porous article is united to the member by being packed in the cavity of said matrix and the biodegradable and bioabsorbable bioactive porous article is partly exposed from said matrix. 
     
     
         3 . The organic-inorganic complex implant article described in  claim 2 , wherein the matrix is formed into a shape of any one of a rectangular prism shape having cavity inlets on its all four upper, lower, left and right sides, an annular shape having a cavity inside thereof, and a cylindrical shape having a cavity inside thereof and two or more cavity inlets arranged on the peripheral face. 
     
     
         4 . The organic-inorganic complex implant article described in  claim 1 , wherein the biodegradable and bioabsorbable member is a skin layer comprising a biodegradable and bioabsorbable polymer containing a bioactive bioceramics powder, and said skin layer is united by superposing on a part of the surface of the biodegradable and bioabsorbable bioactive porous article in a block shape. 
     
     
         5 . The organic-inorganic complex implant article described in  claim 1 , wherein the biodegradable and bioabsorbable bioactive porous article further comprises an ossification factor.