Manufacture Process

Abstract

The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.

1 . A process for preparing an iron(III)-based phosphate adsorbent comprising iron(III) oxide-hydroxide, starch and sucrose, said process comprising:
 (i) reacting an aqueous solution of iron(III) salt with an aqueous base at a pH from between 6 and 10 in the presence of starch to form a precipitate;   (ii) isolating the precipitate formed according to step (i);   (iii) suspending the isolated precipitate from step (ii) in an aqueous solution;   (iv) adding sucrose and optionally at least one excipient selected from a preservative and a binder; and   (v) fluidized spray drying the solution from step (iv) to yield an iron(III)-based phosphate adsorbent as a dry powder.