US2012148590A1PendingUtilityA1

Cell-permeable peptide inhibitors of the jnk signal transduction pathway

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Assignee: BONNY CHRISTOPHEPriority: Oct 12, 1999Filed: Sep 25, 2011Published: Jun 14, 2012
Est. expiryOct 12, 2019(expired)· nominal 20-yr term from priority
A61K 38/00C07K 14/4743C07K 2319/00C07K 2319/10
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Claims

Abstract

The invention provides cell-permeable peptides that bind to JNK protein and inhibit JNK-mediated effects in JNK-expressing cells.

Claims

exact text as granted — not AI-modified
1 .- 37 . (canceled) 
     
     
         38 . A D-enantiomeric peptide comprising the amino acid sequence of SEQ ID NO: 8, wherein said peptide facilitates transport across a biological membrane. 
     
     
         39 . A transport protein comprising a D-enantiomeric peptide, said D-enantiomeric peptide consisting of the amino acid sequence of SEQ ID NO: 8. 
     
     
         40 . A polypeptide comprising the peptide of  claim 38  and a protein covalently bound to said peptide. 
     
     
         41 . A transport protein consisting of a D-enantiomeric peptide, said D-enantiomeric peptide consisting of the amino acid sequence of SEQ ID NO: 8.

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