Adhesive Suture Structure and Methods of Using the Same

Abstract

According to an aspect of the present disclosure, a surgical suture needle assembly is provided including an elongate tube defining a lumen through at least a portion of a length thereof; and a wound treatment material contained within the lumen of the suture structure. The present disclosure further provides for methods of using the surgical suture needle assembly in anastomotic procedures and the like.

1 - 37 . (canceled) 
     
     
         38 . A surgical suture, comprising:
 a monofilament suture structure defining a solid elongate core having a perimeter; and   a wound treatment material deposited around the perimeter and dispersed throughout the solid elongate core of the suture structure, wherein the wound treatment material comes into contact with tissue upon penetration of the tissue with the suture structure during a suturing procedure.   
     
     
         39 . The surgical suture according to  claim 38 , wherein the suture structure is fabricated from one of a bio-absorbable material and a non-absorbable material. 
     
     
         40 . The surgical suture according to  claim 39 , wherein the non-absorbable material of the suture structure is selected from the group consisting of silk, polyamides, polyesters, polyethylene terephthalate, polyacrylonitrile, polyethylene, polypropylene, silk cotton, and linen. 
     
     
         41 . The surgical suture according to  claim 39 , wherein the bio-absorbable material of the suture structure is selected from the group consisting of a natural collagenous material, and synthetic resins including those derived from glycolic acid, glycolide, lactic acid, lactide, dioxanone, polycaprolactone, epsilon-caprolactone, trimethylene carbonate. 
     
     
         42 . The surgical suture according to  claim 38 , wherein the wound treatment material is selected from the group consisting of an adhesive, a hemostat, a sealant, and combinations thereof. 
     
     
         43 . The surgical suture according to  claim 42 , wherein the adhesives include materials selected from the group consisting of protein derived, aldehyde-based adhesive materials, and cyanoacrylate-based materials. 
     
     
         44 . The surgical suture according to  claim 42 , wherein the sealants include materials selected from the group consisting of fibrin sealants, collagen-based tissue sealants, synthetic polymer-based tissue sealants, and synthetic polyethylene glycol-based, hydrogel materials. 
     
     
         45 . The surgical suture according to  claim 42 , wherein the hemostats include materials selected from the group consisting of fibrin-based materials, collagen-based materials, oxidized regenerated cellulose-based materials, gelatin-based topical materials, and fibrinogen-thrombin combination materials. 
     
     
         46 . The surgical suture according to  claim 42 , wherein the wound treatment material includes a therapeutic agent. 
     
     
         47 . The surgical suture according to  claim 46 , wherein the therapeutic agents include antibiotics including materials selected from the group consisting of gentamycin sulfates, erythromycins, and derivatized glycopeptides. 
     
     
         48 . The surgical suture according to  claim 42 , wherein the wound treatment materials include at least one growth promoting factor. 
     
     
         49 . The surgical suture according to  claim 48 , wherein the growth promoting factor includes materials selected from the group consisting of fibroblast growth factor, bone growth factor, epidermal growth factor, platelet derived growth factor, macrophage derived growth factor, alveolar derived growth factor, monocyte derived growth factor, and magainin. 
     
     
         50 . The surgical suture according to  claim 42 , wherein the wound treatment material is pressure activated. 
     
     
         51 . The surgical suture according to  claim 38 , further comprising a suture needle operatively connected to an end of the suture structure.